Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.
World J Gastrointest Surg. Aug 27, 2026; 18(8): 118103
Published online Aug 27, 2026. doi: 10.4240/wjgs.118103
Published online Aug 27, 2026. doi: 10.4240/wjgs.118103
Long-term outcomes following successful treatment of acute mesenteric ischemic event: A population-based observational study
Karri Kase, Marko Murruste, Department of Surgery, Tartu University Hospital, Tartu 50406, Estonia
Karri Kase, Annika Reintam Blaser, Kadri Tamme, Peep Talving, Marko Murruste, Institute of Clinical Medicine, University of Tartu, Tartu 50090, Estonia
Merli Koitmäe, Institute of Mathematics and Statistics, University of Tartu, Tartu 50090, Estonia
Merli Koitmäe, Institute of Genomics, University of Tartu, Tartu 50090, Estonia
Annika Reintam Blaser, Centre of Intensive Care Medicine, Luzerner Kantonsspital, Lucerne 6000, Luzern, Switzerland
Kadri Tamme, Department of Anesthesiology and Intensive Care, Tartu University Hospital, Tartu 50406, Estonia
Peep Talving, Department of Surgery, North Estonia Medical Centre, Tallinn 13419, Estonia
Author contributions: Kase K drafted the manuscript; Koitmäe M performed the statistical analysis; Reintam Blaser A, Tamme K, Talving P, and Murruste M assisted with writing the manuscript; Kase K, Koitmäe M, Reintam Blaser A, Tamme K, Talving P, and Murruste M conceptualized the study; and all authors critically revised the manuscript and approved its final version.
Supported by the Estonian Research Council, No. PRG1255.
Institutional review board statement: Ethical approval for the study was obtained from the Estonian Committee on Bioethics and Human Research (No. 1.1-12/2736).
Informed consent statement: The Ethics Committee gave approval to do the study without consent.
Conflict-of-interest statement: All authors declare no conflict of interest in publishing the manuscript.
STROBE statement: The authors have read the STROBE Statement – checklist of items, and the manuscript was prepared and revised according to the STROBE Statement – checklist of items.
Data sharing statement: Study data can be made available upon reasonable request for future collaborative analyses.
Corresponding author: Karri Kase, MD, Lecturer, Department of Surgery, Tartu University Hospital, Puusepa 8, Tartu 50406, Estonia. karri.kase@kliinikum.ee
Received: December 25, 2025
Revised: February 6, 2026
Accepted: April 10, 2026
Published online: August 27, 2026
Processing time: 234 Days and 22.7 Hours
Revised: February 6, 2026
Accepted: April 10, 2026
Published online: August 27, 2026
Processing time: 234 Days and 22.7 Hours
Core Tip
Core Tip: We observed overall improved survival for patients with superior mesenteric vein occlusion; however, for patients discharged alive, survival rates were higher in the case of nonocclusive mesenteric ischemia and superior mesenteric vein occlusion. The risk factors for mortality in all patients included age, disability, comorbidity, and lack of antithrombotic therapy. Our data suggest long-term survival benefit in patients with superior mesenteric artery thrombosis, who receive antithrombotic therapy following discharge. Future prospective studies should assess different regimens of antithrombotic therapy.