Music therapy combined with anesthesia recovery care boosts anesthesia recovery in colorectal cancer patients undergoing laparoscopic radical resection

doi:10.4240/wjgs.v17.i9.106301

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Sep 27, 2025 (publication date) through Sep 27, 2025

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World Journal of Gastrointestinal Surgery

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1948-9366

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastrointest Surg. Sep 27, 2025; 17(9): 106301
Published online Sep 27, 2025. doi: 10.4240/wjgs.v17.i9.106301

Table 1 Comparative analysis of baseline characteristics between groups, n (%)

Baseline characteristics		Control group (n = 60)	Observation group (n = 60)	t/χ²	P value
Gender	Male	35 (58.33)	33 (55.00)	0.023	0.887
Gender	Female	25 (41.67)	27 (45.00)	0.023	0.887
Age (year, mean ± SD)		56.80 ± 2.30	57.30 ± 1.96	0.372	0.708
Mean BMI (kg/m², mean ± SD)		24.28 ± 2.08	24.13 ± 2.01	0.459	0.639
Mean duration of anesthesia (hour, mean ± SD)		3.18 ± 0.32	3.25 ± 0.36	0.814	0.418
ASA classification	I	29 (48.33)	30 (50.00)	0.473	0.492
ASA classification	II	31 (51.67)	30 (50.00)	0.473	0.492
Pathological staging	II	35 (58.33)	37 (61.67)	0.454	0.501
Pathological staging	III	25 (41.67)	23 (38.33)	0.454	0.501

BMI: Body mass index; ASA: American Society of Anesthesiologists.

Full Size Table

Table 2 Comparison of anesthesia recovery quality between groups, mean ± SD

Categories	Control group (n = 60)	Observation group (n = 60)	t	P value
Time to regain consciousness	32.83 ± 2.44	23.19 ± 1.73	8.599	0.000
Extubation time	41.83 ± 3.54	33.86 ± 2.60	7.532	0.000
Length of stay in the Postanesthesia care unit	56.83 ± 4.36	40.38 ± 3.18	9.229	0.000

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Table 3 Comparison of vital signs between groups, mean ± SD

Indicators		Control group (n = 60)	Observation group (n = 60)
HR (beats/minute)	Before anesthesia	72.15 ± 8.25	72.40 ± 8.45
HR (beats/minute)	During the recovery period	77.55 ± 9.50^a	87.30 ± 10.40^b
SBP (mmHg)	Before anesthesia	130.85 ± 8.35	131.20 ± 9.00
SBP (mmHg)	During the recovery period	139.55 ± 9.80^a	151.55 ± 9.25^b
DBP (mmHg)	Before anesthesia	82.45 ± 10.75	81.95 ± 9.60
DBP (mmHg)	During the recovery period	85.65 ± 10.05^a	95.40 ± 9.60^b

^aP < 0.05 vs pre-anesthesia level.

^bP < 0.05 vs control group.

HR: Heart rate; SBP: Systolic blood pressure; DBP: Diastolic blood pressure.

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Table 4 Comparison of stress response between groups, mean ± SD

Indicators		Control group (n = 60)	Observation group (n = 60)
Cor (nmol/L)	Before anesthesia	163.47 ± 22.69	163.35 ± 22.79
Cor (nmol/L)	24 hours postoperative	210.13 ± 26.40^a	184.08 ± 21.50^b
Ald (pmol/L)	Before anesthesia	122.33 ± 20.57	123.51 ± 22.41
Ald (pmol/L)	24 hours postoperative	175.27 ± 23.13^a	150.41 ± 25.05^b
NE (ng/mL)	Before anesthesia	186.38 ± 13.53	186.03 ± 13.99
NE (ng/mL)	24 hours postoperative	290.38 ± 13.20^a	240.31 ± 12.98^b
AD (ng/L)	Before anesthesia	150.33 ± 8.27	152.38 ± 9.00
AD (ng/L)	24 hours postoperative	260.11 ± 9.11^a	198.40 ± 10.17^b

^aP < 0.05 vs pre-anesthesia level.

^bP < 0.05 vs control group.

Cor: Cortisol; Ald: Aldosterone; NE: Norepinephrine; AD: Adrenaline.

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Table 5 Comparison of postoperative recovery quality between groups, mean ± SD

Categories	Control group (n = 60)	Observation group (n = 60)	t	P value
Cognitive	12.57 ± 1.22	21.30 ± 2.30	21.035	0.000
Activities of daily living	7.14 ± 0.89	10.21 ± 1.11	13.007	0.000
Emotional	6.17 ± 0.84	9.14 ± 1.05	13.277	0.000
Nociceptive	4.27 ± 0.73	7.94 ± 0.98	17.967	0.000
Physiologic	15.54 ± 1.41	25.32 ± 2.33	22.155	0.000

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Table 6 Comparison of complication rates between groups, n (%)

Complications	Control group (n = 60)	Observation group (n = 60)	χ²	P value
Arrhythmia	2 (3.33)	0 (0.00)	-	-
Shivering	3 (5.00)	0 (0.00)	-	-
Hypothermia	9 (15.00)	3 (5.00)	-	-
Emergence agitation	5 (8.33)	2 (3.33)	-	-
Nausea/vomiting	5 (8.33)	1 (1.67)	-	-
Total	24 (40.00)	6 (10.00)	7.853	0.000

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Citation: Zheng Y, Ni HF, Shi Y, Cui DQ, Wu ZZ, Ling YF, He SQ, Qin XY. Music therapy combined with anesthesia recovery care boosts anesthesia recovery in colorectal cancer patients undergoing laparoscopic radical resection. World J Gastrointest Surg 2025; 17(9): 106301
URL: https://www.wjgnet.com/1948-9366/full/v17/i9/106301.htm
DOI: https://dx.doi.org/10.4240/wjgs.v17.i9.106301