Application effect of linaclotide capsules combined with compound polyethylene glycol in colonoscopy bowel preparation

Table 1 Patient characteristic among the three groups

Group	Gender		Age (year)	Reason for colonoscopy
	Male	Female		Abdominal discomfort	Black stool/bloody stool	Constipation	Routine check-up	Other
A (n = 29)	16	13	52.77 ± 6.32	5	7	8	6	3
B (n = 50)	26	24	53.65 ± 7.14	14	12	11	7	6
C (n = 37)	18	19	53.29 ± 8.48	10	6	9	5	7
Statistic	0.28		1.012	3.636
P value	0.869		0.367	0.888

Table 2 Comparison of Boston bowel preparation scale scores among the three groups

Group	Left colon	Transverse colon	Right colon	Total score
A (n = 29)	2.78 ± 0.45	2.70 ± 0.51	2.41 ± 0.55	7.75 ± 1.23
B (n = 50)	2.74 ± 0.41	2.69 ± 0.48	2.32 ± 0.59	7.69 ± 1.14
C (n = 37)	2.76 ± 0.49	2.56 ± 0.64	2.35 ± 0.66	7.66 ± 1.31
Statistic	0.203	0.954	1.042	1.446
P value	0.816	0.388	0.356	0.240

Table 3 Comparison of bowel preparation completion rate and detection of positive lesions among the three groups, n (%)

Group	Bowel preparation completion rate	Adenoma detection rate	Polyp detection rate
A (n = 29)	28 (96.55)	6 (20.69)	10 (34.48)
B (n = 50)	45 (90.00)	19 (38.00)	25 (50.00)
C (n = 37)	36 (97.30)	12 (32.43)	14 (37.84)
Statistic	2.453	2.539	2.243
P value	0.293	0.281	0.326

Table 4 Comparison of colonoscopy examination time among the three groups

Group	Insertion time (minute)	Withdrawal time (minute)
A (n = 29)	6.03 ± 4.34	7.45 ± 2.91
B (n = 50)	6.12 ± 3.60	9.02 ± 3.54
C (n = 37)	5.33 ± 2.42	6.86 ± 2.66a
Statistic	0.541	3.717
P value	0.584	0.027

^aP < 0.05, statistically significant difference compared with group B.

Table 5 Comparison of adverse reaction rates among the three groups, n (%)

Group	Nausea	Abdominal pain	Palpitations	Vomiting	Dizziness	Total occurrence rate
A (n = 29)	1 (3.45)	0 (0.00)	1 (3.45)	1 (3.45)	1 (3.45)	2 (6.90)
B (n = 50)	5 (10.00)	2 (4.00)	1 (2.00)	5 (10.00)	3 (6.00)	10 (20.00)
C (n = 37)	1 (2.70)	0 (0.00)	0 (0.00)	1 (2.70)	0 (0.00)	1 (2.70)a
Statistic						7.116
P value						0.029

^aP < 0.05, statistically significant difference compared with group B.

Table 6 Comparison of patient satisfaction among the three groups, n (%)

Group	Satisfied	Neutral	Not satisfied	Total satisfaction rate
A (n = 29)	16 (55.17)	10 (34.48)	3 (10.34)	26 (89.66)
B (n = 50)	26 (52.00)	16 (32.00)	8 (16.00)	42 (84.00)
C (n = 37)	22 (59.46)	14 (37.84)	1 (2.70)	36 (97.30)
Statistic				4.059
P value				0.398