Efficacy and safety of enhanced recovery after surgery protocol on liver transplantation: A meta-analysis

Table 1 Characteristics of the included studies

Ref.	Region	Design	Intervention	Sample size	Age (years)	Sex (male/female)	Follow-up	Outcomes	Newcastle-Ottawa Scale score
Brustia et al[2]	France	PCS	ERAS	10	60.1± 3.4	8/2	> 1 year	(1), (2), (3), (4), (5)	7
			SC	20	58.2 ± 3.18	17/3
Findlay et al[17]	United States	RCT	ERAS	39	51.0 ± 11.5	22/17	NR	(1)	-
			SC	39	53.1 ± 8.5	24/15
Hillings et al[20]	Denmark	RCS	ERAS	270	48.3 ± 12	158/112	329 days ± 87 days	(1), (3), (4)	8
			SC	64	51 ± 10	39/25
Jin et al[19]	China	RCS	ERAS	130	49 ± 10.25	82/48	1 year	(3), (4)	8
			SC	120	45 ± 11	68/52
Kara et al[18]	Turkey	RCS	ERAS	20	42 ± 3.28	12/8	NR	(1), (2), (3);	9
			SC	40	48 ± 2.57	27/13
King et al[22]	United States	PCS	ERAS	141	58 ± 2.5	78/28	1 year	(1), (2), (5)	8
			SC	106	58 ± 2.25	40/14
Rao et al[3]	China	RCT	ERAS	54	52.4 ± 15.2	40/14	3 months	(1), (2), (3), (4), (5)	-
			SC	74	55.8 ± 14.3	58/16
Xu et al[21]	China	RCS	ERAS	40	49.5 ± 4.2	35/5	2 months	(1), (2), (3), (4), (5)	8
			SC	53	53 ± 3	46/7

ERAS: Enhanced recovery after surgery; NR: Not reported; PCS: prospective cohort study; RCS: Retrospective cohort study; RCT: Randomized controlled trial; SC: Standard care; (1): Intensive care unit duration; (2): Length of hospitalization; (3): Overall complications; (4): Mortality; (5): Readmissions within 30 days.