Clinical Trials Study
Copyright ©The Author(s) 2025.
World J Gastrointest Surg. Jul 27, 2025; 17(7): 106560
Published online Jul 27, 2025. doi: 10.4240/wjgs.v17.i7.106560
Table 1 Comparison of general data among the three groups, n (%)

Purse-string suture group
Cross-suture group
Vertical interrupted suture group
P value
Cases101010
Comorbidities0.672
    None9 (90.00)7 (70.00)6 (60.00)
    Hypertension1 (10.00)2 (20.00)2 (20.00)
    Diabetes0 (0.00)1 (10.00)1 (10.00)
    Coronary artery disease0 (0.00)0 (0.00)1 (10.00)
Primary disease0.986
    Colon cancer3 (30.00)2 (20.00)3 (30.00)
    Rectal cancer6 (60.00)7 (70.00)6 (60.00)
    Intestinal obstruction1 (10.00)1 (10.00)1 (10.00)
Gender0.171
    Male4 (40.00)8 (80.00)8 (80.00)
    Female6 (60.00)2 (20.00)2 (20.00)
Table 2 Comparison of general data among the three groups, mean ± SD

Purse-string suture group
Cross-suture group
Vertical interrupted suture group
P value
Cases101010
Age, years58.20 ± 10.1959.40 ± 8.8260.00 ± 14.170.876
Height, m1.64 ± 0.081.65 ± 0.071.64 ± 0.100.940
Weight, kg56.65 ± 6.6260.10 ± 6.9860.90 ± 8.330.402
BMI, kg/m221.01 ± 1.9021.87 ± 1.5622.45 ± 2.520.298
Preoperative albumin level, g/L41.23 ± 3.6541.48 ± 2.9342.13 ± 3.680.834
Time interval before reversal, months6.40 ± 2.505.60 ± 2.276.30 ± 1.880.687
Table 3 Comparison of intraoperative and postoperative recovery indicators among the three groups, M (QL-QU)

Purse-string suture group
Cross-suture group
Vertical interrupted suture group
P value
Cases101010
Surgical time, minutes53.00 (50.00-56.25)59.00 (53.75-67.00)60.00 (55.25-67.00)0.107
Intraoperative blood loss, mL21.00 (18.75-35.00)20.00 (20.00-50.00)22.50 (20.00-42.50)0.588
Time to start liquid diet, days3.00 (3.00-4.25)3.00 (3.00-3.00)3.50 (3.00-5.00)0.061
Time to first bowel movement, days3.00 (2.75-3.00)3.00 (3.00-3.00)3.00 (3.00-3.00)0.850
Postoperative hospitalization duration, days8.00 (6.75-10.00)7.00 (6.25-9.00)7.00 (6.00-8.50)0.082
Suture removal time, days7.00 (6.00-8.00)7.00 (7.00-7.00)7.00 (7.00-8.50)0.004
Wound healing time, days21.00 (20.00-22.00)21.00 (19.00-22.00)24.00 (23.00-27.25)0.002
Hospitalization costs, CNY38792.50 (34118.25-43267.25)37503.00 (33699.25-40873.50)38645.00 (33237.75-42444.75)0.756
Table 4 Comparison of postoperative recovery indicators among the three groups, M (QL-QU)

Purse-string suture group
Cross-suture group
Vertical interrupted suture group
P value
Cases101010
Postoperative white blood cell count, 109/L6.7950 (5.7675-7.6050)5.9150 (5.0250-7.1750)6.0050 (4.5525-7.5900)0.477
Postoperative CRP level, mg/L30.5000 (25.0000-37.7500)37.0000 (26.0000-42.0000)58.0000 (50.0000-70.0000)0.000
Postoperative hemoglobin level, g/L109.5000 (89.7500-132.0000)113.5000 (103.0000-120.7500)112.0000 (97.2500-120.7500)0.935
Postoperative albumin level, g/L37.5000 (34.7500-41.0000)35.6000 (34.0000-37.0000)35.5000 (33.7500-37.2500)0.290
Table 5 Comparison of postoperative visual analog scale pain scores among the three groups, mean ± SD

Purse-string suture group
Cross-suture group
Vertical interrupted suture group
P value
Cases101010
12 hours post-surgery4.00 ± 0.474.10 ± 0.315.40 ± 0.690.000
1 day post-surgery3.50 ± 0.523.20 ± 0.424.80 ± 0.630.000
2 days post-surgery3.30 ± 0.482.90 ± 0.314.10 ± 0.560.000
3 days post-surgery2.60 ± 0.512.40 ± 0.513.30 ± 0.480.000
Table 6 Comparison of postoperative safety indicators among the three groups, n (%)

Purse-string suture group
Cross-suture group
Vertical interrupted suture group
P value
Cases101010
SSI004 (40.00)0.010
Anastomotic leak000-
Intestinal obstruction001 (10.00)0.355
Incisional hernia000-
Pulmonary infection2 (20.00)1 (10.00)2 (20.00)0.535
Suture site bleeding2 (20.00)2 (20.00)3 (30.00)0.830
Death000-