Retrospective Study
Copyright ©The Author(s) 2025.
World J Gastrointest Surg. Apr 27, 2025; 17(4): 100476
Published online Apr 27, 2025. doi: 10.4240/wjgs.v17.i4.100476
Table 1 General clinical data and surgery-related indexes of the two groups (n = 109), mean ± SD
Basic information
Observation group (n = 50)
Control group (n = 59)
P value
SexMale23290.743
Female2730
Age (years)< 60 years30350.943
≥ 60 years2024
TNM stageI570.744
II1422
III3130
Accompanying diseasesHigh blood pressure13180.603
Diabetes680.808
Coronary heart disease550.783
BMI (kg/m2)24.69 ± 5.7125.66 ± 6.060.393
Operation time (minutes)171.1 ± 11.0161.4 ± 9.10.000
Intraoperative blood volume (mL)154.6 ± 21.9179.8 ± 23.50.000
Postoperative hospital stays (days)6.43 ± 0.637.59 ± 2.190.000
Postoperative drainage time (days)5.18 ± 0.405.31 ± 0.780.296
Time to anal exhaust (days)2.49 ± 0.332.68 ± 0.310.004
Length of resected specimens (cm)37.8 ± 1.538.3 ± 1.60.083
Average number of lymph nodes dissected25.8 ± 2.425.9 ± 1.60.691
Table 2 Comparison of inflammatory factor levels between the two groups, mean ± SD
Group
TNF-α (ng/mL)
CRP (ng/mL)
Preoperative
1 day after operation
3 days after operation
Preoperative
1 day after operation
3 days after operation
Observation group8.04 ± 0.7157.47 ± 2.1912.14 ± 0.2417.23 ± 1.36160.40 ± 9.6481.43 ± 4.26
Control group10.25 ± 1.1558.60 ± 1.9130.21 ± 1.4216.98 ± 4.36165.18 ± 11.2108.54 ± 3.24
P value0.7390.0250.0000.1720.0130.000
Table 3 Complications of patients with right-sided colon cancer in the two groups, n (%)
Group
Intestinal obstruction
Anastomotic leakage
Incision infection
Lung infection
Total
Observation group (n = 50)2 (4.0)2 (4.0)2 (4.0)6(12)12 (24.0)
Control group (n = 59)3 (5.0)1 (1.7)7 (11.9)8(13.6)19 (32.2)
P value1.0000.8840.2550.8080.344
Table 4 Comparison of distant metastasis rate, recurrence rate, and mortality between the two groups, n (%)
Group
Distant metastasis incidence rate at 2 years
Recurrence rate at 2 years
Mortality at 2 years
Observation group7 (14.0)8 (16.0)6 (12.0)
Control group9 (15.3)11 (18.6)10 (16.9)
P value0.8540.7170.467