Therapeutic effectiveness and influencing factors of laparoscopic appendectomy with mesoappendix dissection in the treatment of acute appendicitis

Table 1 Patient general information

General information	Control group (n = 72)	Observation group (n = 78)	χ2/t	P value
Sex (male/female)	42/30	44/34	0.057	0.812
Age (years)	48.36 ± 6.18	49.03 ± 7.56
Body mass index (kg/m2)	23.58 ± 2.37	24.32 ± 2.55
Time from acute onset to admission (hour)	24.01 ± 3.16	23.64 ± 3.24
Family medical history (without/with)	64/8	67/11	0.303	0.582

Measurement data were statistically described as (mean ± SD).

Table 2 Therapeutic effectiveness of the two groups, n (%)

Therapeutic effectiveness	Control group (n = 72)	Observation group (n = 78)	χ2	P value
Markedly effective	25 (34.72)	35 (44.87)
Effective	35 (48.61)	39 (50.00)
Ineffective	12 (16.67)	4 (5.13)
Total	60 (83.33)	74 (94.87)	5.231	0.022

Table 3 Surgical indices of the two groups

Surgical indices	Control group (n = 72)	Observation group (n = 78)	t	P value
Operation time (minute)	50.76 ± 6.42	43.96 ± 4.97	7.285	< 0.001
Intraoperative blood loss (mL)	37.00 ± 7.38	24.64 ± 6.24	11.104	< 0.001
Hospital stay (day)	7.24 ± 2.63	5.47 ± 1.73	4.905	< 0.001

Measurement data were statistically described as (mean ± SD).

Table 4 Postoperative recovery indices of the two groups

Postoperative recovery index	Control group (n = 72)	Observation group (n = 78)	t	P value
Time to ambulation (hour)	27.90 ± 4.80	22.37 ± 3.98	7.703	< 0.001
Time to gastrointestinal function recovery (day)	3.42 ± 1.32	2.15 ± 0.90	6.930	< 0.001
Time to food intake (day)	3.76 ± 1.27	2.69 ± 1.02	5.709	< 0.001

Measurement data were statistically described as (mean ± SD).

Table 5 Incidence rate of adverse events in two groups, n (%)

Postoperative recovery indexes	Control group (n = 72)	Observation group (n = 78)	χ2	P value
Postoperative bleeding	5 (6.94)	2 (2.56)
Pelvic infection	3 (4.17)	1 (1.28)
Puncture site infection	3 (4.17)	0 (0.00)
Ileus	1 (1.39)	0 (0.00)
Total	12 (16.67)	3 (3.85)	6.838	0.009

Table 6 Multivariate analysis of factors influencing patient efficacy

Factor	β	SE	Wald	P value	Exp (β)	95%CI
Sex	-0.088	0.566	0.024	0.876	0.915	0.302-2.777
Age	-0.015	0.044	0.122	0.726	0.985	0.904-1.073
Body mass index (kg/m2)	-0.109	0.116	0.883	0.347	0.897	0.714-1.126
Time from acute onset to admission (hour)	0.144	0.105	1.902	0.168	1.155	0.941-1.418
Family medical history	-0.214	0.916	0.054	0.816	0.808	0.134-4.861
Preoperative TNF-α (ng/L)	-0.872	0.941	0.859	0.354	0.418	0.066-2.643
Preoperative IL-6 (pg/mL)	-0.007	0.030	0.058	0.809	0.993	0.937-1.052
Preoperative CRP (mg/L)	0.065	0.115	0.319	0.572	1.067	0.852-1.335
Treatment modality	1.214	0.621	3.820	0.051	3.368	0.997-11.380

TNF-α: Tumor necrosis factor-α; IL-6: Interleukin-6; CRP: C-reactive protein.