Retrospective Study
Copyright ©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Surg. Mar 27, 2025; 17(3): 103516
Published online Mar 27, 2025. doi: 10.4240/wjgs.v17.i3.103516
Therapeutic effectiveness and influencing factors of laparoscopic appendectomy with mesoappendix dissection in the treatment of acute appendicitis
Jiang Yuan, Qiang Liu, Bo-Yu Wu
Jiang Yuan, Qiang Liu, Bo-Yu Wu, Department of General Surgery, Shangrao Municipal Hospital, Shangrao 334000, Jiangxi Province, China
Author contributions: Yuan J designed and performed the research; Yuan J and Wu BY designed the research and supervised the report; Yuan J, Liu Q and Wu BY collected and analyzed data; All authors approved the final manuscript.
Institutional review board statement: This study was approved by the Ethic Committee of Shangrao Municipal Hospital on June 21, 2024.
Informed consent statement: Patients were not required to give informed consent to the study because the analysis used anonymous clinical data that were obtained after each patient agreed to treatment by written consent.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Data sharing statement: No additional data are available.
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Bo-Yu Wu, Assistant Professor, Department of General Surgery, Shangrao Municipal Hospital, No. 7 Ziyang Avenue, Xinzhou District, Shangrao 334000, Jiangxi Province, China. 15270327885@163.com
Received: November 21, 2024
Revised: December 17, 2024
Accepted: January 11, 2025
Published online: March 27, 2025
Processing time: 94 Days and 18.4 Hours
Core Tip

Core Tip: At present, relevant research focusing on the efficacy and influencing factors of laparoscopic appendectomy with mesoappendix dissection in treating patients with acute appendicitis is limited. In this study, 150 patients who are suffering from acute appendicitis were enrolled. Comparative analyses regarding the clinical application of conventional laparoscopic appendectomy and laparoscopic appendectomy with mesoappendix dissection were performed among these patients, taking into account therapeutic effectiveness, surgical parameters, postoperative rehabilitation, the occurrence rate of adverse events, and serum inflammatory factors. Finally, we concluded that laparoscopic appendectomy with mesoappendix dissection, when applied to treat patients with acute appendicitis, can enhance the treatment efficacy and surgical outcomes, facilitating patients’ postoperative recovery, decreasing the incidence of adverse events, and averting the excessive increase of inflammatory markers, including tumor necrosis factor-α, interleukin-6, and C-reactive protein triggered by surgical stimuli. Hence, this approach shows great potential in clinical application.