Therapeutic effectiveness and influencing factors of laparoscopic appendectomy with mesoappendix dissection in the treatment of acute appendicitis

Core Tip

Core Tip: At present, relevant research focusing on the efficacy and influencing factors of laparoscopic appendectomy with mesoappendix dissection in treating patients with acute appendicitis is limited. In this study, 150 patients who are suffering from acute appendicitis were enrolled. Comparative analyses regarding the clinical application of conventional laparoscopic appendectomy and laparoscopic appendectomy with mesoappendix dissection were performed among these patients, taking into account therapeutic effectiveness, surgical parameters, postoperative rehabilitation, the occurrence rate of adverse events, and serum inflammatory factors. Finally, we concluded that laparoscopic appendectomy with mesoappendix dissection, when applied to treat patients with acute appendicitis, can enhance the treatment efficacy and surgical outcomes, facilitating patients’ postoperative recovery, decreasing the incidence of adverse events, and averting the excessive increase of inflammatory markers, including tumor necrosis factor-α, interleukin-6, and C-reactive protein triggered by surgical stimuli. Hence, this approach shows great potential in clinical application.