Clinical Trials Study
Copyright ©The Author(s) 2025.
World J Gastrointest Surg. Mar 27, 2025; 17(3): 100143
Published online Mar 27, 2025. doi: 10.4240/wjgs.v17.i3.100143
Table 1 Comparison of surgical-related indicators among three groups of patients, mean ± SD
Groups
Cases (n)
Intraoperative blood loss (mL)
Surgery duration (minute)
Postoperative time to first flatus (day)
Time to ambulation (day)
Postoperative hospital stay (day)
Control40398.14 ± 74.21301.25 ± 45.155.25 ± 1.313.94 ± 1.2116.91 ± 4.23
Open surgery25205.13 ± 69.32265.13 ± 37.434.13 ± 1.153.06 ± 0.8015.15 ± 3.71
Laparoscopic surgery45177.31 ± 55.15231.25 ± 27.773.43 ± 1.022.87 ± 0.7413.15 ± 3.15
F value131.99837.75626.15614.48610.973
P value0.0000.0000.0000.0000.000
Table 2 Comparison of trauma stress response indicators among three groups of patients, mean ± SD
Groups
Cases (n)
ET (ng/L)
NO (μmol/L)
CRP (mg/L)
Before
After 12 hours
Before
After 12 hours
Before
After 12 hours
Control401.05 ± 0.321.80 ± 0.5810.08 ± 3.1720.13 ± 3.4021.15 ± 1.2163.12 ± 12.58
Open surgery251.04 ± 0.391.65 ± 0.5310.11 ± 3.1518.05 ± 2.4521.30 ± 1.2559.12 ± 11.37
Laparoscopic surgery451.01 ± 0.351.39 ± 0.5110.03 ± 3.1116.13 ± 2.1121.34 ± 1.1850.10 ± 10.33
F value0.1496.2320.00622.9250.27914.367
P value0.8620.0020.994< 0.0010.757< 0.001
Table 3 Comparison of complication incidence rates among three groups of patients, n (%)
Groups
Cases (n)
Anastomotic fistula
Incision infection
Pulmonary infection
Dumping syndrome
Abdominal infection
Total incidence
Control402 (5.00)3 (7.50)0 (0)1 (2.50)2 (5.00)8 (20.00)
Open surgery253 (12.00)4 (16.00)1 (4.00)2 (8.00)4 (16.00)14 (56.00)
Laparoscopic surgery457 (15.56)1 (2.22)0 (0)5 (11.11)5 (11.11)18 (40.00)
Control and laparoscopic group χ2/P value8.904/0.002
Control and laparoscopic group χ2/P value3.989/0.045
Control and laparoscopic χ2/P value1.657/0.197
Table 4 Comparison of long-term prognosis follow-up survey among three groups of patients, n (%)
Group
Cases (n)
6 months post-discharge
1 year after discharge
2 years after discharge
Control4036 (90.00)28 (70.00)22 (55.00)
Open surgery2524 (96.00)23 (92.00)20 (80.00)
Laparoscopic surgery4544 (97.78)41 (91.11)34 (75.56)
Control and open χ2/P value0.780/0.3774.406/0.0354.205/0.040
Control and laparoscopic χ2/P value2.313/0.1286.176/0.0123.980/0.046
Open and laparoscopic χ2/P value0.183/0.6680.016/0.8980.180/0.671