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©The Author(s) 2025.
World J Gastrointest Surg. Dec 27, 2025; 17(12): 113364
Published online Dec 27, 2025. doi: 10.4240/wjgs.v17.i12.113364
Published online Dec 27, 2025. doi: 10.4240/wjgs.v17.i12.113364
Table 1 Between-group comparisons of laboratory parameters (mean ± SD, ng/L)
| Group | Observation group (n = 28) | Control group (n = 27) | t value | P value | |
| IL-6 | Before intervention | 35.18 ± 9.67 | 35.72 ± 9.43 | 0.100 | 0.835 |
| After intervention | 9.81 ± 2.19a | 32.35 ± 9.91a | 11.745 | 0.000 | |
| IL-4 | Before intervention | 6.58 ± 0.31 | 6.63 ± 0.08 | 0.812 | 0.420 |
| After intervention | 0.74 ± 0.06a | 4.02 ± 0.74a | 23.383 | 0.000 | |
| IL-2 | Before intervention | 4.25 ± 0.82 | 4.53 ± 0.67 | 1.384 | 0.172 |
| After intervention | 0.55 ± 0.13a | 1.96 ± 0.21a | 30.060 | 0.000 | |
| IL-17A | Before intervention | 10.29 ± 0.56 | 10.34 ± 0.23 | 0.430 | 0.669 |
| After intervention | 3.25 ± 1.03a | 8.15 ± 0.84a | 19.294 | 0.000 | |
| IFN-γ | Before intervention | 5.36 ± 0.49 | 5.51 ± 0.73 | 0.898 | 0.373 |
| After intervention | 0.69 ± 0.17a | 2.58 ± 0.28a | 30.385 | 0.000 | |
| TNF-α | Before intervention | 3.07 ± 0.51 | 3.24 ± 0.18 | 1.636 | 0.108 |
| After intervention | 1.71 ± 0.42a | 2.73 ± 0.33a | 9.990 | 0.000 | |
| IL-10 | Before intervention | 6.37 ± 0.25 | 6.51 ± 0.79 | 0.893 | 0.376 |
| After intervention | 1.31 ± 0.32a | 3.59 ± 0.91a | 12.458 | 0.000 | |
Table 2 Within-group comparisons of cytokine levels (mean ± SD, ng/L)
| Group | Cytokine | Before intervention | After intervention | t value | P value |
| Observation group (n = 28) | IL-6 | 35.18 ± 9.67 | 9.81 ± 2.19 | 13.540 | 0.000 |
| IL-4 | 6.58 ± 0.31 | 0.74 ± 0.06 | 97.869 | 0.000 | |
| IL-2 | 4.25 ± 0.82 | 0.55 ± 0.13 | 23.582 | 0.000 | |
| IL-17A | 10.29 ± 0.56 | 3.25 ± 1.03 | 31.775 | 0.000 | |
| IFN-γ | 5.36 ± 0.49 | 0.69 ± 0.17 | 47.645 | 0.000 | |
| TNF-α | 3.07 ± 0.51 | 1.71 ± 0.42 | 10.893 | 0.000 | |
| IL-10 | 6.37 ± 0.25 | 1.31 ± 0.32 | 65.934 | 0.000 | |
| Control group (n = 27) | IL-6 | 35.72 ± 9.43 | 32.35 ± 9.91 | 1.280 | 0.206 |
| IL-4 | 6.63 ± 0.08 | 4.02 ± 0.74 | 18.221 | 0.000 | |
| IL-2 | 4.53 ± 0.67 | 1.96 ± 0.21 | 19.019 | 0.000 | |
| IL-17A | 10.34 ± 0.23 | 8.15 ± 0.84 | 13.066 | 0.000 | |
| IFN-γ | 5.51 ± 0.73 | 2.58 ± 0.28 | 19.473 | 0.000 | |
| TNF-α | 3.24 ± 0.18 | 2.73 ± 0.33 | 7.050 | 0.000 | |
| IL-10 | 6.51 ± 0.79 | 3.59 ± 0.91 | 12.591 | 0.000 |
Table 3 Between-group comparisons of nutritional status
| Group | Observation group (n = 28) | Control group (n = 27) | χ2/t | P value | ||
| CONUT, n (%) | Before intervention | > 2 points | 15 (53.57) | 21 (77.78) | 3.562 | 0.059 |
| ≤ 2 points | 13 (46.43) | 6 (22.22) | ||||
| After intervention | > 2 points | 3 (10.71) | 18 (66.67) | 18.232 | 0.000 | |
| ≤ 2 points | 25 (89.29) | 9 (33.33) | ||||
| PA (mean ± SD, mg/L) | Before intervention | 265.28 ± 52.31 | 265.74 ± 52.86 | 0.032 | 0.974 | |
| After intervention | 141.56 ± 37.38a | 260.97 ± 61.84a | 8.703 | 0.000 | ||
Table 4 Within-group comparisons of nutritional status
| Group | Indicator | Before intervention | After intervention | t/χ2 | P value |
| Observation group (n = 28) | CONUT > 2, n (%) | 15 (53.57) | 3 (10.71) | 11.790 | < 0.001 |
| PA (mean ± SD, mg/L) | 265.28 ± 52.31 | 141.56 ± 37.38a | 10.183 | < 0.001 | |
| Control group (n = 27) | CONUT > 2, n (%) | 21 (77.78) | 18 (66.67) | 0.831 | 0.362 |
| PA (mean ± SD, mg/L) | 265.74 ± 52.86 | 260.97 ± 61.84a | 0.310 | 0.758 |
Table 5 Comparison of gastrointestinal function recovery time (mean ± SD)
| Group | Exhaust time (hour) | Recovery time of bowel sounds (day) | Improvement time of abdominal distension (day) |
| Observation group (n = 28) | 31.97 ± 4.35 | 2.84 ± 0.57 | 3.37 ± 0.43 |
| Control group (n = 27) | 45.71 ± 4.78 | 3.81 ± 0.68 | 4.31 ± 0.56 |
| t value | 11.157 | 5.741 | 6.998 |
| P value | 0.000 | 0.000 | 0.000 |
- Citation: Ma HY, Chen YW, Liu X, Zhang MM, Tan BB. Modified Pingwei Baohe decoction improves postoperative recovery in gastric cancer patients. World J Gastrointest Surg 2025; 17(12): 113364
- URL: https://www.wjgnet.com/1948-9366/full/v17/i12/113364.htm
- DOI: https://dx.doi.org/10.4240/wjgs.v17.i12.113364
