Influence factors of clinical effects on patients with early gastric cancer: A retrospective study

Table 1 Assignment table of independent variables

Variable variables	Assignment
Diameter of tumor	0: Tumor diameter < 20 mm; 1: Tumor diameter ≥ 20 mm
Tumor location	0: Lower stomach; 1: Upper middle stomach
Ulcer formation	0: No; 1: Yes
Depth of penetration	0: Mucosal; 1: Submucosa
Pathological type	0: Differentiated type; 1: Undifferentiated type
Lymph node metastasis	0: No; 1: Yes

Table 2 Clinical characteristics of early gastric cancer patients

Characteristics		Number of patients	CRG (n = 143)	NCRG (n = 30)	χ2	P value
Gender	Male	126	108	18	3.020	0.082
	Female	47	35	12
Age (years)	≥ 65	66	53	13	0.413	0.520
	< 65	107	90	17
Family history of stomach cancer	Yes	41	36	5	0.993	0.319
	No	132	107	25
Tumor diameter (mm)	≥ 20	59	42	17	8.221	0.004
	< 20	114	101	13
Tumor location	Upper and middle part of stomach	119	93	26	5.404	0.020
	Lower part of stomach	54	50	4
Ulcer formation	Yes	66	47	19	9.755	0.002
	No	107	96	11
Depth of infiltration	Mucous membrane layer	97	88	9	10.014	0.002
	Submucosa	76	55	21
History of Helicobacter pylori infection	Yes	44	36	8	0.029	0.865
	No	129	107	22
Pathological type	Differentiation type	85	78	7	9.666	0.002
	Undifferentiated type	88	65	23
Consolidation of depressed lesions	Yes	106	91	15	1.943	0.163
	No	67	52	15
Consolidation of mucosal lesions	Yes	118	98	20	0.040	0.842
	No	55	45	10
Lymph node metastasis	Yes	77	55	22	12.209	0.001
	No	96	88	8

CRG: Curative resection group; NCRG: Non-curative resection group.

Table 3 Comparison of clinical efficacy in the study population

Group	Curative resection rate (%)	En bloc resection rate (%)
ESD group (n = 87)	80.46	94.25
Surgical group (n = 86)	84.88	100
χ2	0.591	3.248
P value	0.442	0.072

ESD: Endoscopic submucosal dissection.

Table 4 Multivariate logistic regression analysis of factors affecting non-curative resection in early gastric cancer patients

Factors	Regression coefficient	Standard error	Z value	Wald χ2	P value	OR value	95%CI
Diameter of tumor	1.146	0.412	2.783	7.746	0.005	3.15	1.40-7.05
Tumor location	1.251	0.565	2.215	4.904	0.027	3.50	1.16-10.58
Ulcer formation	1.261	0.419	3.012	9.071	0.003	3.53	1.55-8.01
Depth of penetration	1.317	0.434	3.036	9.217	0.002	3.73	1.60-8.74
Pathological type	1.317	0.434	3.036	9.217	0.002	3.73	1.60-8.74
Lymph node metastasis	1.482	0.447	3.313	10.976	0.001	4.40	1.83-10.57

OR: Odds ratio; CI: Confidence interval.

Table 5 Predictive value of each factor for non-curative resection in early gastric cancer patients

Characteristic	AUC value	Sensitivity	Specificity
Diameter of tumor	0.636	0.567	0.706
Tumor location	0.608	0.867	0.35
Ulcer formation	0.652	0.633	0.671
Depth of infiltration	0.658	0.7	0.615
Pathological type	0.656	0.767	0.545
Lymph node metastasis	0.674	0.733	0.615

AUC: Area under the curve.