Prognostic value of acute liver injury in cirrhotic patients after the transjugular intrahepatic portosystemic shunt procedure

Figure 1 Kaplan-Meier curves for cumulative incidence of overt hepatic encephalopathy and overall survival after the transjugular intrahepatic portosystemic shunt procedure. A and B: Kaplan-Meier curves for cumulative incidence of overt hepatic encephalopathy after the transjugular intrahepatic portosystemic shunt (TIPS) procedure in all patients (A), and in acute liver injury (ALI) and no-ALI groups (B); C and D: Kaplan-Meier curves for overall survival after TIPS in all patients (C), and in ALI and no-ALI groups (D). HE: Hepatic encephalopathy.

Figure 2 Nomogram for the prediction and receiver operating characteristic curve of prediction of 1-, 2- and 3-year overall survival. A-C: Nomogram for the prediction of 1-, 2- and 3-year overall survival (OS) after transjugular intrahepatic portosystemic shunt procedure (A), training set (B) and validation set (C); D and E: Receiver operating characteristic curve predicting one-, two- and three-year OS in the training set (D) and validation set (E). HCC: Hepatocellular carcinoma; MELD: Model for End-Stage Liver Disease; OS: Overall survival; AUC: Area under the receiver operating characteristic curve.

Figure 3 Decision curve analysis to predict survival for cirrhotic patients after transjugular intrahepatic portosystemic shunt procedure. A-C: 1-, 2- and 3-year survival rates for training set; D-F: 1-, 2- and 3-year survival rates for validation set. OS: Overall survival.

Figure 4 Kaplan-Meier curve for overall survival of patients after the transjugular intrahepatic portosystemic shunt procedure in low-risk and high-risk groups stratified according to the nomogram prediction model. A-C: The survival curves for the total set (A), the training cohort (B), and validation set (C), based on an optimal cutoff point for low- and high-risk groups. OS: Overall survival.