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World J Gastrointest Surg. Aug 27, 2026; 18(8): 122207
Published online Aug 27, 2026. doi: 10.4240/wjgs.122207
Published online Aug 27, 2026. doi: 10.4240/wjgs.122207
Prognostic factors of sepsis following laparoscopic hiatal hernia repair
Hong Yu, Jun-Ying Xu, Ya-Ru Zhang, Xiao-Bing Zhou, Department of Nephrology, The Second People’s Hospital of Hunan Province/Brain Hospital of Hunan Province, Changsha, Hunan Province 410007, China
Han-Rong Zuo, Department of Clinical Medicine, Hunan University of Chinese Medicine, Changsha, Hunan Province 410007, China
Zhi Li, Department of Critical Care Medicine, The Second People’s Hospital of Hunan Province/Brain Hospital of Hunan Province, Changsha, Hunan Province 410007, China
Author contributions: Yu H and Li Z conceived and designed the study; Yu H, Xu JY, and Zhang YR were responsible for data collection and patient management; Zhou XB and Zuo HR performed the statistical analysis and interpreted the results; Yu H drafted the manuscript, with critical revisions provided by all co-authors. All authors approved the final version and agreed to be accountable for all aspects of the work.
AI contribution statement: The authors declare that no AI tools were used in the study design, data collection, data analysis, interpretation of results, manuscript writing, or language editing.
Institutional review board statement: The study was reviewed and approved by the Ethics Committee of the Brain Hospital of Hunan Province (The Second People’s Hospital of Hunan Province), No. 2025K095.
Informed consent statement: The requirement for informed consent was waived by the Ethics Committee of the Brain Hospital of Hunan Province (The Second People’s Hospital of Hunan Province) because this retrospective study used anonymized clinical data.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Data sharing statement: The datasets used and/or analyzed during the current study are available from the corresponding author upon reasonable request.
Corresponding author: Zhi Li, MD, Associate Chief Physician, Department of Critical Care Medicine, The Second People’s Hospital of Hunan Province/Brain Hospital of Hunan Province, No. 427 Furong Middle Road, Changsha, Hunan Province 410007, China.
Received: June 5, 2026
Revised: July 18, 2026
Accepted: August 10, 2026
Published online: August 27, 2026
Processing time: 72 Days and 16 Hours
Revised: July 18, 2026
Accepted: August 10, 2026
Published online: August 27, 2026
Processing time: 72 Days and 16 Hours
Core Tip
Core Tip: Postoperative sepsis occurs in 19.6% of patients undergoing laparoscopic hiatal hernia repair, with acute kidney injury (AKI) complicating 42.9% of septic cases. All in-hospital deaths occurred in the AKI subgroup, with stage 3 AKI carrying 80.0% mortality. American Society of Anesthesiologists class ≥ III, operative time > 180 minutes, and preoperative hypoalbuminemia independently predict sepsis. Combined Sequential Organ Failure Assessment and Kidney Disease: Improving Global Outcomes staging achieves superior mortality discrimination (area under the curve 0.924). Early AKI recognition and preoperative nutritional optimization are critical for improving outcomes.