He Q, Xue JM, Weng JF, Li XN, Zhang CX. Incidence and risk factors of poor wound healing following emergency surgery for intestinal tuberculosis. World J Gastrointest Surg 2026; 18(8): 120625 [DOI: 10.4240/wjgs.120625]
Corresponding Author of This Article
Cai-Xia Zhang, MD, Academic Fellow, Department of Outpatient and Day Care Unit, The Eighth Medical Center of Chinese PLA General Hospital, No. 17 Heishanhu Jia, Haidian District, Beijing 100091, China. zcx851026@163.com
Research Domain of This Article
Gastroenterology & Hepatology
Article-Type of This Article
research-article
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He Q, Xue JM, Weng JF, Li XN, Zhang CX. Incidence and risk factors of poor wound healing following emergency surgery for intestinal tuberculosis. World J Gastrointest Surg 2026; 18(8): 120625 [DOI: 10.4240/wjgs.120625]
Qian He, The Senior Department of General Surgery, Chinese PLA General Hospital, Beijing 100091, China
Juan-Min Xue, Xia-Nan Li, The Senior Department of Tuberculosis, Chinese PLA General Hospital, Beijing 100091, China
Jian-Feng Weng, Department of General Surgery, The Eighth Medical Center of Chinese PLA General Hospital, Beijing 100091, China
Cai-Xia Zhang, Department of Outpatient and Day Care Unit, The Eighth Medical Center of Chinese PLA General Hospital, Beijing 100091, China
Co-first authors: Qian He and Juan-Min Xue.
Co-corresponding authors: Xia-Nan Li and Cai-Xia Zhang.
Author contributions: He Q and Xue JM conceptualized and designed the study, performed surgical management of patients, and made critical revisions of the manuscript, they contributed equally to this article, they are the co-first authors of this manuscript; Xue JM participated in patient recruitment, clinical data collection, and interpretation of tuberculosis-related findings; Zhang CX coordinated outpatient follow-up, collected wound assessment data, and conducted statistical analysis; Li XN supervised the overall study, contributed to the interpretation of tuberculosis-related findings, and gave final approval of the manuscript; Li XN and Zhang CX contributed equally to this article, they are the co-corresponding authors of this manuscript; and all authors reviewed and approved the final version of the manuscript.
Institutional review board statement: This study was approved by the Medical Ethics Committee of the Eighth Medical Center of Chinese PLA General Hospital, approval No. S-2026-007-01.
Informed consent statement: The informed consent was waived by the Institutional Review Board. All patient data were strictly anonymized to maintain confidentiality.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Data sharing statement: De-identified participant data are available from the corresponding author, Caixia Zhang, upon reasonable request at zcx851026@163.com.
Corresponding author: Cai-Xia Zhang, MD, Academic Fellow, Department of Outpatient and Day Care Unit, The Eighth Medical Center of Chinese PLA General Hospital, No. 17 Heishanhu Jia, Haidian District, Beijing 100091, China. zcx851026@163.com
Received: March 3, 2026 Revised: April 15, 2026 Accepted: June 1, 2026 Published online: August 27, 2026 Processing time: 166 Days and 15.5 Hours
Core Tip
Core Tip: Intestinal tuberculosis is often complicated by obstruction, perforation, or hemorrhage; thus requiring surgical intervention under emergency settings, but little systematic investigation of risk factors for poor wound healing in this subset exists. In our study we observed the incidence of poor wound healing (19.1%) after emergency intestinal tuberculosis surgery, 63.6% of them were diagnosed as surgical site infection. Five independent risk factors were determined by multivariate logistic regression analysis: Age ≥ 60 years, body mass index < 18.5 kg/m2, diabetes mellitus history, serum albumin concentration < 30 g/L and C-reactive protein > 50 mg/L. Therefore, clinicians should screen these parameters in preoperative evaluation and take targeted interventions (nutritional optimization, glycemic control and anti-inflammatory therapy) to reduce complications and achieve better outcomes.
