Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.
World J Gastrointest Surg. Jul 27, 2026; 18(7): 121776
Published online Jul 27, 2026. doi: 10.4240/wjgs.v18.i7.121776
Published online Jul 27, 2026. doi: 10.4240/wjgs.v18.i7.121776
Clinical application of remimazolam benzenesulfonate in elderly patients undergoing laparoscopic cholecystectomy under intravenous general anesthesia
Qi-Wei Wang, Shuan-Cheng Bai, Affiliated Baotou Clinical College of Inner Mongolia Medical University, Baotou 014040, Inner Mongolia Autonomous Region, China
Lan Wu, Affiliated Inner Mongolia Clinical College of Inner Mongolia Medical University, Hohehot 010017, Inner Mongolia Autonomous Region, China
Zhi-Qiang Wang, Jia Zhang, Department of Anesthesiology, Baotou Central Hospital, Baotou 014040, Inner Mongolia Autonomous Region, China
Author contributions: Wang QW and Wu L conceived the study; Wang ZQ and Zhang J conducted the methodology and investigation, prepared the original draft of the manuscript, and performed the statistical analysis; Bai SC contributed to the review and editing of the manuscript.
Supported by Public Hospital Research Joint Fund Science and Technology Project, No. 2023GLLH0236.
Institutional review board statement: The study was approved by the Ethics Committee of Baotou Central Hospital [Approval No. KYLL2024(Ethics)082].
Clinical trial registration statement: This study is registered at https://www.chictr.org.cn/index.html. The registration identification number is ChiCTR2600117283.
Informed consent statement: All participants provided written informed consent. The study was conducted in accordance with the Declaration of Helsinki.
Conflict-of-interest statement: The authors declare no competing interests.
CONSORT 2010 statement: The authors have read the CONSORT 2010 Statement, and the manuscript was prepared and revised according to the CONSORT 2010 Statement.
Data sharing statement: All patient data can be requested by sending an email to the corresponding author.
Corresponding author: Shuan-Cheng Bai, Full Professor, Affiliated Baotou Clinical College of Inner Mongolia Medical University, No. 61 Huancheng Road, Donghe District, Baotou 014040, Inner Mongolia Autonomous Region, China. 13947236426@163.com
Received: April 1, 2026
Revised: April 13, 2026
Accepted: May 14, 2026
Published online: July 27, 2026
Processing time: 117 Days and 20 Hours
Revised: April 13, 2026
Accepted: May 14, 2026
Published online: July 27, 2026
Processing time: 117 Days and 20 Hours
Core Tip
Core Tip: This study demonstrates that remimazolam benzenesulfonate offers more stable hemodynamics and a lower incidence of adverse reactions compared to propofol during total intravenous anesthesia in elderly patients undergoing laparoscopic cholecystectomy. Additionally, remimazolam provides benefits in early postoperative recovery, cognitive function, and pain control, though these advantages diminish over time. These findings suggest that remimazolam may be a promising alternative for anesthesia management in this patient population.