Preoperative prediction model for 30 days biliary events after laparoscopic cholecystectomy

doi:10.4240/wjgs.v18.i7.121443

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Publication Name

World Journal of Gastrointestinal Surgery

ISSN

1948-9366

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Retrospective Cohort Study

Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Gastrointest Surg. Jul 27, 2026; 18(7): 121443
Published online Jul 27, 2026. doi: 10.4240/wjgs.v18.i7.121443

Preoperative prediction model for 30 days biliary events after laparoscopic cholecystectomy

Zhong-Peng Chen

Zhong-Peng Chen, Guangzhou Panyu District Maternal and Child Health Hospital (Affiliated Hospital Group of Guangdong Medical University Panyu HeXian Memorial Hospital), Guangzhou 510000, Guangdong Province, China

Author contributions: Chen Z designed the study, collected and analyzed the data, performed the statistical analysis, interpreted the results, drafted and revised the manuscript, and approved the final version of the article.

AI contribution statement: Portions of this manuscript were polished and translated using the DeepSeek AI tool. The generation of research data, interpretation of results, and derivation of conclusions were conducted entirely without AI assistance. All content generated by AI was subject to rigorous manual review and revision by the authors.

Institutional review board statement: The study was reviewed and approved by the Ethics Committee of Guangzhou Panyu District Maternal and Child Health Hospital (Approval No. 2025111122).

Informed consent statement: All study participants, or their legal guardians, provided informed written consent prior to study inclusion.

Conflict-of-interest statement: The author declares that there are no conflicts of interest related to this study.

STROBE statement: The authors have read the STROBE Statement—checklist of items, and the manuscript was prepared and revised according to the STROBE Statement—checklist of items.

Data sharing statement: No additional data are available.

Corresponding author: Zhong-Peng Chen, MD, Guangzhou Panyu District Maternal and Child Health Hospital (Affiliated Hospital Group of Guangdong Medical University Panyu HeXian Memorial Hospital), No. 2 Qinghe East Road, Shiqiao, Panyu District, Guangzhou 510000, Guangdong Province, China. 932831906@qq.com

Received: March 26, 2026
Revised: May 6, 2026
Accepted: June 2, 2026
Published online: July 27, 2026
Processing time: 124 Days and 23.4 Hours

Core Tip

Core Tip: Clinically relevant biliary events within 30 days after laparoscopic cholecystectomy, such as retained common bile duct (CBD) stones, bile leak, cholangitis, and biliary pancreatitis, may necessitate endoscopic retrograde cholangiopancreatography (ERCP), drainage, or unplanned readmission. In this single-center retrospective cohort of 287 patients, 29 patients (10.1%) experienced the primary outcome. A parsimonious preoperative nomogram based on total bilirubin and a height-normalized CBD/height index showed robust discrimination in the original split-sample analysis, supportive bootstrap-based internal validation, and stable performance in a sensitivity analysis excluding patients who underwent preoperative ERCP.