Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.
World J Gastrointest Surg. Jul 27, 2026; 18(7): 119514
Published online Jul 27, 2026. doi: 10.4240/wjgs.v18.i7.119514
Published online Jul 27, 2026. doi: 10.4240/wjgs.v18.i7.119514
Immune-nutritional score-based prognostic model for predicting postoperative complications and survival in gastric cancer
Wen-Lou Liu, Hao-Nan Liu, Meng-Han Cao, Hong-Mei Wang, Xiao-Bing Qin, Juan-Juan Tang, Yang Zhao, Yan Ge, Zheng-Xiang Han, Department of Oncology, The Affiliated Hospital of Xuzhou Medical University, Xuzhou 221002, Jiangsu Province, China
Author contributions: Liu WL and Liu HN contributed equally to the conceptualization and design of the study; Liu WL was primarily responsible for data collection and analysis; Liu HN played a key role in interpreting the results and drafting the manuscript; Cao MH, Wang HM, and Qin XB contributed to data analysis and interpretation, and participated in writing and revising the manuscript, also provided valuable feedback on the study’s methodology and analysis; Tang JJ and Zhao Y contributed to the project’s overall management and provided critical feedback on the study’s design and implementation, also contributed to writing and revising the manuscript; Ge Y and Han ZX contributed to the overall management of the project and provided critical feedback on the design and implementation of the research; and all authors played significant roles in the development of the study and approved the final version of the manuscript.
AI contribution statement: This paper did not use any AI tools.
Supported by Pengcheng Talents-Key Medical Talent Training Project, No. XWRCHT20220068.
Institutional review board statement: This study was approved by the Medical Ethics Committee of the Affiliated Hospital of Xuzhou Medical University, approval No. XYFY2023-KL277-01.
Informed consent statement: The requirement for patients’ informed consent for this study was waived due to its retrospective nature.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Data sharing statement: The data used and/or analyzed during the current study are available from the corresponding author.
Corresponding author: Zheng-Xiang Han, PhD, Department of Oncology, The Affiliated Hospital of Xuzhou Medical University, No. 99 Huaihai West Road, Quanshan District, Xuzhou 221002, Jiangsu Province, China. 18652288252@163.com
Received: March 10, 2026
Revised: March 31, 2026
Accepted: May 14, 2026
Published online: July 27, 2026
Processing time: 139 Days and 0.7 Hours
Revised: March 31, 2026
Accepted: May 14, 2026
Published online: July 27, 2026
Processing time: 139 Days and 0.7 Hours
Core Tip
Core Tip: This study proposes an immune-nutritional score, derived from routinely available laboratory parameters, to evaluate the risk of postoperative complications and survival in patients with gastric cancer. By integrating indicators of nutritional status, immune function, and systemic inflammation, immune-nutritional score showed improved predictive performance compared with single markers. It may provide a practical approach for preoperative risk assessment and support individualized perioperative management. Further validation in larger, prospective cohorts is warranted to confirm its generalizability and clinical utility.