Xiao PZ, Zou WB, Xu JW, Wang T, Wang P, Ma JJ, Zheng CH. Impact of ozonated water on perianal infectious diseases: A retrospective study. World J Gastrointest Surg 2026; 18(7): 119424 [DOI: 10.4240/wjgs.v18.i7.119424]
Corresponding Author of This Article
Chun-Hua Zheng, Associate Chief Physician, Department of Gastrointestinal and Hernia Surgery, Guihang Guiyang Hospital, No. 420 Huanghe Road, Huaxi District, Guiyang 550025, Guizhou Province, China. skykillsci@163.com
Research Domain of This Article
Gastroenterology & Hepatology
Article-Type of This Article
research-article
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Xiao PZ, Zou WB, Xu JW, Wang T, Wang P, Ma JJ, Zheng CH. Impact of ozonated water on perianal infectious diseases: A retrospective study. World J Gastrointest Surg 2026; 18(7): 119424 [DOI: 10.4240/wjgs.v18.i7.119424]
Pei-Zhen Xiao, Jia-Wen Xu, Tian Wang, Ping Wang, Jiao-Jiao Ma, Chun-Hua Zheng, Department of Gastrointestinal and Hernia Surgery, Guihang Guiyang Hospital, Guiyang 550025, Guizhou Province, China
Wen-Bing Zou, Department of Laboratory Medicine, Guihang Guiyang Hospital, Guiyang 550025, Guizhou Province, China
Author contributions: Xiao PZ, Zou WB, Xu JW, Wang T, Wang P, and Ma JJ contributed to conceiving the research and analyzing data; Xiao PZ and Zheng CH designed the research, wrote the first manuscript, conducted the analysis and provided guidance for the research. All authors approval the final manuscript.
AI contribution statement: The authors declare that no AI tools were used in the development or writing of this manuscript and take full responsibility for its integrity, accuracy, and originality.
Supported by General Medical 2022 Annual Research Fund Project, No. TYYLKYJJ-2 022-034.
Institutional review board statement: This retrospective study was approved by the Ethics Committee of Guihang Guiyang Hospital (Approval No. GHGYYYLL-KY-202501A).
Informed consent statement: All the study subjects provided informed consent.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Data sharing statement: No additional data are available.
Corresponding author: Chun-Hua Zheng, Associate Chief Physician, Department of Gastrointestinal and Hernia Surgery, Guihang Guiyang Hospital, No. 420 Huanghe Road, Huaxi District, Guiyang 550025, Guizhou Province, China. skykillsci@163.com
Received: April 14, 2026 Revised: May 18, 2026 Accepted: May 25, 2026 Published online: July 27, 2026 Processing time: 104 Days and 1.4 Hours
Core Tip
Core Tip: If a perianal abscess is not treated promptly or is improperly managed, it may progress into a chronic infection and form an anal fistula, seriously threatening patient health. Surgical intervention remains the primary treatment approach. Although surgery provides reliable short-term efficacy, it is highly invasive and involves prolonged wound healing. Ozone, owing to its strong oxidizing properties, has been increasingly used in clinical practice and has demonstrated beneficial effects in promoting wound healing. However, few studies have investigated the use of ozonated water for treating infected wounds in the perianal region, which presents unique management challenges. Therefore, this study primarily evaluated the therapeutic efficacy of ozonated water for infected perianal wounds.
