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World J Gastrointest Surg. Jun 27, 2026; 18(6): 117526
Published online Jun 27, 2026. doi: 10.4240/wjgs.117526
Published online Jun 27, 2026. doi: 10.4240/wjgs.117526
Clinical features, diagnosis, and treatment of colorectal cap polyposis
Li-Na Shan, Si-Jie Yin, Bing-Jun Bai, Kai Xu, Sheng Dai, Wei Zhou, Department of Colorectal Surgery, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou 310016, Zhejiang Province, China
Jin-Lin Shan, The Second School of Clinical Medicine, Zhejiang Chinese Medical University, Hangzhou 310053, Zhejiang Province, China
Co-first authors: Li-Na Shan and Jin-Lin Shan.
Co-corresponding authors: Sheng Dai and Wei Zhou.
Author contributions: Shan LN and Shan JL contributed equally to this study in clinical data collection and manuscript drafting as first authors; Yin SJ coordinated pathological staining; Bai BJ validated histopathological findings; Xu K performed database management; Dai S and Zhou W conceived the study, provided clinical supervision, critically revised the manuscript, and serve as corresponding authors.
Supported by National Natural Science Foundation of China, No. 82373163.
Institutional review board statement: The study was reviewed and approved by the Ethics Committee of Sir Run Run Shaw Hospital, Zhejiang University School of Medicine (Approval No. 2024-0669).
Informed consent statement: Written informed consent was obtained from all patients for the use of anonymized clinical data and publication of this report.
Conflict-of-interest statement: All authors declare no conflicts of interest related to this work.
Data sharing statement: Anonymized data supporting the findings of this study are available from the corresponding author upon reasonable request.
Corresponding author: Wei Zhou, PhD, Chief Physician, Department of Colorectal Surgery, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, No. 3 East Qingchun Road, Hangzhou 310016, Zhejiang Province, China. weizhou_srrsh@zju.edu.cn
Received: December 15, 2025
Revised: March 5, 2026
Accepted: April 8, 2026
Published online: June 27, 2026
Processing time: 189 Days and 18.7 Hours
Revised: March 5, 2026
Accepted: April 8, 2026
Published online: June 27, 2026
Processing time: 189 Days and 18.7 Hours
Core Tip
Core Tip: Cap polyposis is a rare inflammatory colorectal disorder characterized by fibrinopurulent-capped polyps. Clinicians frequently misdiagnose it as inflammatory bowel disease. This study retrospectively analyzed seven patients and established a stepwise management algorithm based on lesion distribution, size, and symptoms. Endoscopic or transanal resection achieved sustained symptomatic relief in all treated patients. Protein-losing enteropathy resolved rapidly after definitive surgical intervention.