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World J Gastrointest Surg. May 27, 2026; 18(5): 118473
Published online May 27, 2026. doi: 10.4240/wjgs.v18.i5.118473
Published online May 27, 2026. doi: 10.4240/wjgs.v18.i5.118473
Cancer-related fatigue and functional gastrointestinal disorders after total gastrectomy: A case report
Bing Lu, Department of Gastroenterology, Xiangya Changde Hospital, Changde 415000, Hunan Province, China
Kai Wen, Department of Rehabilitation Medicine, Xiangya Changde Hospital, Changde 415000, Hunan Province, China
Author contributions: Lu B is responsible for research design, data organization, and paper writing and revision; Wen K coordinated the research and revised the final draft. All authors acknowledge the final manuscript and confirm its ethical compliance.
AI contribution statement: No main text was AI-generated; AI not used for language polishing, translation, data analysis or writing; AI not involved in study design/result interpretation; and no AI-generated images.
Informed consent statement: Informed consent was obtained from the patient before the publication of this case report.
Conflict-of-interest statement: The authors declare no competing financial interests.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Corresponding author: Kai Wen, Associate Chief Physician, Research Fellow, Department of Rehabilitation Medicine, Xiangya Changde Hospital, No. 1688 Moon Avenue, Wuling District, Changde 415000, Hunan Province, China. 17607361799@163.com
Received: February 6, 2026
Revised: March 5, 2026
Accepted: March 17, 2026
Published online: May 27, 2026
Processing time: 110 Days and 4.8 Hours
Revised: March 5, 2026
Accepted: March 17, 2026
Published online: May 27, 2026
Processing time: 110 Days and 4.8 Hours
Core Tip
Core Tip: Cancer-related fatigue and functional gastrointestinal disorders (FGID) frequently coexist in patients after gastric cancer (GC) surgery, particularly following total gastrectomy. Their clinical manifestations are insidious, heterogeneous, and often overlooked once tumor recurrence has been excluded. This case underscores the importance of comprehensive differential diagnosis, multidisciplinary management, and holistic symptom assessment that extends beyond oncological surveillance. Early recognition and individualized intervention for cancer-related fatigue and FGIDs are crucial for improving long-term outcomes and enhancing the quality of life in post- GC surgery patients.