Subtotal colectomy with Deloyers colo-anal anastomosis for refractory ulcerative colitis: A case report

doi:10.4240/wjgs.v18.i5.117998

Advanced Search

BPG is committed to discovery and dissemination of knowledge

Home / Archive / Volume 18, Issue 5

This Article

(3)

(1)

(0)

(129)

Peer-Review Report of This Article

CrossCheck and Google Search of This Article

Academic Rules and Norms of This Article

Citation of this article

Corresponding Author of This Article

Research Domain of This Article

Article-Type of This Article

Open-Access Policy of This Article

Times Cited Counts in Google of This Article

Journal Information of This Article

Publication Name

World Journal of Gastrointestinal Surgery

ISSN

1948-9366

Publisher of This Article

Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Case Report

Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Gastrointest Surg. May 27, 2026; 18(5): 117998
Published online May 27, 2026. doi: 10.4240/wjgs.v18.i5.117998

Subtotal colectomy with Deloyers colo-anal anastomosis for refractory ulcerative colitis: A case report

Chuong Dinh Nguyen, Luan Minh Dang, Thuy Thi-Thanh Trinh, Huy Duc Tran, Anh The Phan, Diem Thi-Ngoc Vo, Huyen Duy-Mai Le, Thong Duy Vo, Hoang Huu Bui

Chuong Dinh Nguyen, Thuy Thi-Thanh Trinh, Thong Duy Vo, Hoang Huu Bui, Department of Gastroenterology, University Medical Center Ho Chi Minh City, Ho Chi Minh City 700000, Viet Nam

Chuong Dinh Nguyen, Faculty of Medicine, Chulalongkorn University, Bangkok 10120, Thailand

Luan Minh Dang, Inflammatory Bowel Disease Unit, Department of Gastroenterology, University Medical Center Ho Chi Minh City, Ho Chi Minh City 700000, Viet Nam

Luan Minh Dang, Department of Internal Medicine and Gastro-Hepato Integrated Research Team (GHIRT-002.TCM2025), School of Medicine, University of Medicine and Pharmacy at Ho Chi Minh City, Ho Chi Minh City 700000, Viet Nam

Huy Duc Tran, Department of Gastrointestinal Surgery, University Medical Center Ho Chi Minh City, Ho Chi Minh City 700000, Viet Nam

Huy Duc Tran, Department of General surgery, School of Medicine, University of Medicine and Pharmacy at Ho Chi Minh City, Ho Chi Minh City 700000, Viet Nam

Anh The Phan, Department of Pathology, Cho Ray Hospital, Ho Chi Minh City 700000, Viet Nam

Diem Thi-Ngoc Vo, Department of Histology, Embryology and Pathology, School of Medicine, University of Medicine and Pharmacy at Ho Chi Minh City, Ho Chi Minh 700000, Viet Nam

Huyen Duy-Mai Le, Department of Diagnostic Imaging, University Medical Center Ho Chi Minh City, Ho Chi Minh City 700000, Viet Nam

Thong Duy Vo, Department of Internal Medicine, School of Medicine, University of Medicine and Pharmacy at Ho Chi Minh City, Ho Chi Minh City 700000, Viet Nam

Author contributions: Nguyen CD collected the clinical data, reviewed the literature, and drafted the initial manuscript; Dang LM conceived the study, directly managed the patient’s treatment, and was a major contributor in writing and editing the manuscript; Tran HD performed the surgical procedure and wrote the section on surgical technique; Phan AT and Vo DT performed the histopathological examination and interpretation; Le HD was responsible for the analysis and interpretation of diagnostic imaging; Trinh TT assisted in the post-operative care coordination and critically reviewed the manuscript; Vo TD and Bui HH provided supervision, critically revised the manuscript for important intellectual content, and gave final approval for submission. All authors read and approved the final manuscript.

AI contribution statement: The author solely utilized Google Gemini to enhance the language, clarity, fluency, and grammar of the text written by the author. No AI tools were employed for research design, data analysis, result interpretation, literature search, citation generation, scientific content creation, or chart production/modification. All clinical content, scientific reasoning, and conclusions were original work of the author. The author is fully responsible for the integrity and accuracy of the paper.

Informed consent statement: Informed written consent was obtained from the patient for publication of this report and any accompanying images.

Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.

CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).

Corresponding author: Luan Minh Dang, MD, Lecturer, Inflammatory Bowel Disease Unit, Department of Gastroenterology, University Medical Center Ho Chi Minh City, 215 Hong Bang Street, Cho Lon Ward, Ho Chi Minh City 700000, Viet Nam. luan.dm@umc.edu.vn

Received: December 22, 2025
Revised: January 27, 2026
Accepted: February 25, 2026
Published online: May 27, 2026
Processing time: 158 Days and 6.6 Hours

Core Tip

Core Tip: We report a rare case of refractory ulcerative colitis displaying “differential healing” following prolonged high-dose tofacitinib (10 mg thrice daily) rescue therapy. While the distal colon remained severely inflamed despite clinical remission (clinical-endoscopic discordance), the proximal colon achieved complete mucosal healing. This unique segmental response facilitated a function-preserving subtotal colectomy with Deloyers colo-anal anastomosis, avoiding a permanent stoma or ileal pouch. This case highlights a novel medical-surgical strategy leveraging differential healing to preserve colonic function and quality of life in complex scenarios.