Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.
World J Gastrointest Surg. May 27, 2026; 18(5): 116701
Published online May 27, 2026. doi: 10.4240/wjgs.v18.i5.116701
Published online May 27, 2026. doi: 10.4240/wjgs.v18.i5.116701
Correlation of systemic immune-inflammation and prognostic nutritional indices with pathological characteristics and prognosis in gastric cancer
Qiang Song, Clinical Laboratory, Inner Mongolia Baogang Hospital, Baotou 014010, Inner Mongolia Autonomous Region, China
Hao-Shu Niu, Department of Gastroenterology, Inner Mongolia Baogang Hospital, Baotou 014010, Inner Mongolia Autonomous Region, China
Author contributions: Song Q designed the study, wrote the manuscript, and revised the manuscript; Song Q and Niu HS collected and analyzed the data, participated in collection of the data. All authors approved the final version of the manuscript.
Institutional review board statement: Given the retrospective design and data anonymization, approval from the Ethics Review Committee is waived.
Informed consent statement: As the study used anonymous and pre-existing data, the requirement for the informed consent from patients was waived.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Data sharing statement:
No additional data are available.
Corresponding author: Hao-Shu Niu, MD, Department of Gastroenterology, Inner Mongolia Baogang Hospital, No. 20 Shaoxian Road, Kundulun District, Baotou 014010, Inner Mongolia Autonomous Region, China. niuhaoshu1982@163.com
Received: January 16, 2026
Revised: February 4, 2026
Accepted: March 10, 2026
Published online: May 27, 2026
Processing time: 131 Days and 5.2 Hours
Revised: February 4, 2026
Accepted: March 10, 2026
Published online: May 27, 2026
Processing time: 131 Days and 5.2 Hours
Core Tip
Core Tip: This study validated the correlation of the Systemic Immune-Inflammation Index and Prognostic Nutritional Index with clinicopathological characteristics and prognosis in patients with gastric cancer (GC). Analysis of the collected clinical data from patients with GC revealed that Systemic Immune-Inflammation Index and Prognostic Nutritional Index are effective biological markers for predicting GC prognosis, as they reflect patients’ clinicopathological characteristics and prognosis. The combination of the two further enhances prognostic and diagnostic efficacy, and both are also independent predictors for three-year overall survival in such patients.