Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.
World J Gastrointest Surg. Oct 27, 2026; 18(10): 121503
Published online Oct 27, 2026. doi: 10.4240/wjgs.121503
Published online Oct 27, 2026. doi: 10.4240/wjgs.121503
Predictive value of multi-slice spiral computed tomography tumor diameter and necrotic ratio for very high-risk gastrointestinal stromal tumors
Yang-Chun Gu, Tian-Yu Yang, Ke Zhu, Xiao-Jin Zang, Ying-Di Xie, Department of Radiology, Binhai County People’s Hospital; Jiangsu Vocational College of Medicine, Yancheng 224500, Jiangsu Province, China
Cheng-Li Zhao, Department of Gastroenterology, Binhai County People’s Hospital; Jiangsu Vocational College of Medicine, Yancheng 224500, Jiangsu Province, China
Co-first authors: Yang-Chun Gu and Tian-Yu Yang.
Co-corresponding authors: Xiao-Jin Zang and Ying-Di Xie.
Author contributions: Gu YC and Yang TY contributed equally to study design, data collection and manuscript drafting and they contribute equally to this study as co-first authors; Zang XJ and Xie YD supervised the research and revised the manuscript and they contribute equally to this study as co-corresponding authors; Zhu K and Zhao CL participated in data analysis; and all authors approved the final manuscript.
AI contribution statement: No AI tools were utilized in drafting, data analysis or revision of this manuscript. All contents were independently completed by authors, who bear full responsibility for the integrity and accuracy of the whole work.
Supported by Jiangsu Medical Vocational College Yancheng Health Commission Collaborative Innovation Research Project, No. 202491013.
Institutional review board statement: This study was reviewed and approved by the Institutional Review Board of Binhai County People’s Hospital (Approval No. 2025BYKYLL030).
Informed consent statement: All study participants and their legal guardians provided written informed consent before recruitment.
Conflict-of-interest statement: The authors declare no conflict of interest.
Data sharing statement: No additional data are available.
Corresponding author: Ying-Di Xie, Associate Chief Physician, Research Fellow, Department of Radiology, Binhai County People’s Hospital; Jiangsu Vocational College of Medicine, No. 299 Binhai Seaside Avenue, Yancheng 224500, Jiangsu Province, China.
Received: April 24, 2026
Revised: June 11, 2026
Accepted: June 26, 2026
Published online: October 27, 2026
Processing time: 176 Days and 20.7 Hours
Revised: June 11, 2026
Accepted: June 26, 2026
Published online: October 27, 2026
Processing time: 176 Days and 20.7 Hours
Core Tip
Core Tip: Quantitative multi-slice spiral computed tomography imaging biomarkers may improve the preoperative assessment of gastrointestinal stromal tumor (GIST) aggressiveness. This study demonstrated that maximum tumor diameter combined with necrotic area ratio achieved high predictive performance for identifying very high-risk GISTs, providing practical support for individualized clinical management.