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World J Gastrointest Surg. Oct 27, 2026; 18(10): 121417
Published online Oct 27, 2026. doi: 10.4240/wjgs.121417
Published online Oct 27, 2026. doi: 10.4240/wjgs.121417
Risk factors analysis and management strategy optimization for postoperative complications in neonatal necrotizing enterocolitis: A single-center retrospective study
Sha-Sha Gao, Xin-Xian Guan, Xin-Xin Miu, Sheng-Lin Yu, Xue-Ping Zhu, Department of Neonatology, Children’s Hospital of Soochow University, Suzhou 215000, Jiangsu Province, China
Co-first authors: Sha-Sha Gao and Xin-Xian Guan.
Co-corresponding authors: Sheng-Lin Yu and Xue-Ping Zhu.
Author contributions: Gao SS and Guan XX contributed equally to this study as co-first authors, including study design, data collection, statistical analysis, and manuscript drafting and revision; Yu SL and Zhu XP jointly provided project guidance, conducted quality control, critically revised the manuscript, and took overall responsibility for the study as co-corresponding authors; Miu XX participated in data collation, literature review, and manuscript proofreading. All the authors have read and approved the final version of the manuscript.
AI contribution statement: The authors declare that no AI tools were used in the development or writing of this manuscript and take full responsibility for its integrity, accuracy, and originality.
Institutional review board statement: This study has been reviewed and approved by the Medical Ethics Committee of Children’s Hospital of Soochow University, No. 2026CS028.
Informed consent statement: All the individuals who participated in this study provided their written informed consent prior to study enrolment.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Data sharing statement: No additional data are available.
Corresponding author: Sheng-Lin Yu, MD, Chief Physician, Department of Neonatology, Children’s Hospital of Soochow University, No. 92 Zhongnan Street, Industrial Park, Suzhou 215000, Jiangsu Province, China. wm19711011@sina.com
Received: April 28, 2026
Revised: June 11, 2026
Accepted: July 3, 2026
Published online: October 27, 2026
Processing time: 173 Days and 0.1 Hours
Revised: June 11, 2026
Accepted: July 3, 2026
Published online: October 27, 2026
Processing time: 173 Days and 0.1 Hours
Core Tip
Core Tip: This retrospective study analyzed 62 neonates with necrotizing enterocolitis who underwent laparotomy. Four factors were associated with an increased risk of postoperative complications. These include problems with preoperative blood pressure, long intestinal resection, low postoperative albumin levels, and long-term mechanical ventilation. These findings provide evidence for improving patient management before and after surgery.