Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.
World J Gastrointest Surg. Oct 27, 2026; 18(10): 121410
Published online Oct 27, 2026. doi: 10.4240/wjgs.121410
Published online Oct 27, 2026. doi: 10.4240/wjgs.121410
Serum prealbumin and C-reactive protein levels to evaluate parenteral nutrition efficacy in critically ill patients with gastrointestinal tumors
Tao Zhang, Xiao-Xiao Li, Fen-Fen Xiang, Rong Wu, Zheng-Rong Zhong, Department of Laboratory Medicine, Putuo Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai 200062, China
Qi Zhao, Department of Laboratory Medicine, Shanghai Children’s Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai 200062, China
Co-first authors: Tao Zhang and Xiao-Xiao Li.
Co-corresponding authors: Zheng-Rong Zhong and Qi Zhao.
Author contributions: Zhang T and Li XX contributed equally as co-first authors and they were responsible for study design, data collection, statistical analysis, and manuscript drafting; Zhong ZR and Zhao Q were co-corresponding authors and they were responsible for project supervision, critical revision, and final approval of the manuscript; Xiang FF and Wu R participated in data collection and the literature review; and all authors approved the final version.
AI contribution statement: The authors declare that no AI tools were utilized in the drafting, writing or polishing of this manuscript, and all content was independently completed by the authors, who take full responsibility for the integrity, accuracy and originality of the work.
Supported by Sanghai Putuo Central Hospital Talent Introduction Program, No. 2024-YJRC-09; and Shanghai Putuo Central Hospital Discipline Construction Project, No. 2024xkjs03.
Institutional review board statement: This study has been reviewed and approved by the Ethics Committee of Putuo Hospital, Shanghai University of Traditional Chinese Medicine [Approval No. PTEC-A-2026-5(S)-1].
Informed consent statement: All the individuals who participated in this study provided their written informed consent prior to study enrolment.
Conflict-of-interest statement: The authors declare no conflicts of interest.
Data sharing statement: No additional data are available.
Corresponding author: Qi Zhao, Research Fellow, Department of Laboratory Medicine, Shanghai Children’s Hospital, School of Medicine, Shanghai Jiao Tong University, No. 355 Luding Road, Putuo District, Shanghai 200062, China. zq198502142022@163.com
Received: April 28, 2026
Revised: June 9, 2026
Accepted: June 24, 2026
Published online: October 27, 2026
Processing time: 171 Days and 15.8 Hours
Revised: June 9, 2026
Accepted: June 24, 2026
Published online: October 27, 2026
Processing time: 171 Days and 15.8 Hours
Core Tip
Core Tip: This study demonstrates that dynamic monitoring of serum prealbumin and C-reactive protein levels can effectively assess the nutritional and inflammatory status of critically ill gastrointestinal tumor patients after parenteral nutrition. The combined detection of these two indicators enables precise prediction of parenteral nutrition efficacy, providing a reliable reference for adjusting clinical nutritional support strategies.