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World J Gastrointest Surg. Oct 27, 2026; 18(10): 120648
Published online Oct 27, 2026. doi: 10.4240/wjgs.120648
Published online Oct 27, 2026. doi: 10.4240/wjgs.120648
Whole-course flexible management model for endoscopic submucosal dissection-treated patients for early digestive tract cancer or pre-cancerous lesions: Efficacy and quality-of-life-impact
Jia-Ying Lin, Xiao-Ling Fang, Hui Chen, Qiang Chen, Xiang Jiang, Jiao-E Chen, Ling-Jun Wu, Department of Gastroenterology, Sanmen People’s Hospital, First Affiliated Hospital of Zhejiang University, Sanmenwan Branch, Taizhou 317100, Zhejiang Province, China
Co-corresponding authors: Jiao-E Chen and Ling-Jun Wu.
Author contributions: Lin JY designed the research and wrote the first manuscript; Lin JY, Fang XL, Chen H, Chen Q, and Jiang X contributed to conceiving the research and analyzing data; Chen JE and Wu LJ conducted the analysis and provided guidance for the research as co-corresponding authors; all authors reviewed and approved the final manuscript.
AI contribution statement: The authors declare that no AI tools were used in the development or writing of this manuscript and take full responsibility for its integrity, accuracy, and originality.
Institutional review board statement: This study was approved by the Ethic Committee of Sanmen People’s Hospital, No. 2025-107.
Informed consent statement: Patients were not required to give informed consent to the study because the analysis used anonymous clinical data that were obtained after each patient agreed to treatment by written consent.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Data sharing statement: No additional data are available.
Corresponding author: Ling-Jun Wu, Department of Gastroenterology, Sanmen People’s Hospital, First Affiliated Hospital of Zhejiang University, Sanmenwan Branch, No. 15 Taihe Road, Hairun Street, Sanmen, Taizhou 317100, Zhejiang Province, China.
Received: April 30, 2026
Revised: June 1, 2026
Accepted: June 30, 2026
Published online: October 27, 2026
Processing time: 171 Days and 18 Hours
Revised: June 1, 2026
Accepted: June 30, 2026
Published online: October 27, 2026
Processing time: 171 Days and 18 Hours
Core Tip
Core Tip: This study comparatively analyzed the intervention effects and quality-of-life outcomes of the whole-course flexible management model vs the conventional management model in patients with early digestive tract cancer or precancerous lesions. The analyses indicated that the whole-course flexible management model offered greater clinical benefits than the conventional approach, including enhanced surgical safety, accelerated recovery, reduced negative emotions, alleviated pain, and improved sleep quality and overall quality of life, accompanied by higher nursing satisfaction.