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©The Author(s) 2026. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Surg. Jan 27, 2026; 18(1): 114810
Published online Jan 27, 2026. doi: 10.4240/wjgs.v18.i1.114810
Published online Jan 27, 2026. doi: 10.4240/wjgs.v18.i1.114810
Neutrophil-lymphocyte ratio, albumin-alkaline phosphatase ratio, and bilirubin predict outcomes in hepatectomy hepatolithiasis patients
Jing Yang, Yong-Xin Yang, Qia-Jun Du, Hong-Wei Gao, Ya-Nan Bai, Laboratory Medicine Center, The Second Hospital & Clinical Medical School, Lanzhou University, Lanzhou 730000, Gansu Province, China
Author contributions: Yang J performed the majority of the experiments and wrote the manuscript; Yang YX designed the study and revised the manuscript; Du QJ was involved in analytical tools; Gao HW participated in sample collection; Bai YN served as a scientific advisor and participated in sample collection.
Institutional review board statement: This study was approved by the Medical Ethics Committee of the Second Hospital & Clinical Medical School, Lanzhou University, China, approval No. 2025A-246.
Informed consent statement: All patients provided informed consent.
Conflict-of-interest statement: No benefits in any form have been received or will be received from any commercial party directly or indirectly related to the subject of this article.
Data sharing statement: The technical appendix, statistical code, and dataset are available from the corresponding author.
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Yong-Xin Yang, Laboratory Medicine Center, The Second Hospital & Clinical Medical School, Lanzhou University, No. 82 Cuiyingmen, Chengguan District, Lanzhou 730000, Gansu Province, China. yangyongxinyy@163.com
Received: September 28, 2025
Revised: October 25, 2025
Accepted: November 19, 2025
Published online: January 27, 2026
Processing time: 115 Days and 1.9 Hours
Revised: October 25, 2025
Accepted: November 19, 2025
Published online: January 27, 2026
Processing time: 115 Days and 1.9 Hours
Core Tip
Core Tip: This study primarily compared the clinical data of patients with hepatolithiasis with good and poor prognoses following hepatectomy, analyzed the factors influencing poor prognosis, and identified scientific and reasonable indicators of poor prognosis. The novelty of this study lies in evaluating the peripheral blood levels of neutrophil-to-lymphocyte ratio (NLR), albumin/alkaline phosphatase ratio (ALB/ALP), and total bilirubin (TBIL) levels after hepatectomy and analyzing their individual and combined predictive values for poor prognosis. Notably, the NLR, ALB/ALP, and TBIL levels demonstrated predictive value for poor prognosis following hepatectomy, with high combined predictive efficiency.