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©The Author(s) 2026. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Surg. Jan 27, 2026; 18(1): 114692
Published online Jan 27, 2026. doi: 10.4240/wjgs.v18.i1.114692
Published online Jan 27, 2026. doi: 10.4240/wjgs.v18.i1.114692
Assessing predictive value of contrast-enhanced ultrasound combined with doppler ultrasound for post-transcatheter arterial chemoembolization prognosis in hepatocellular carcinoma
Jia-Jiao Qian, Department of Ultrasound, The Affiliated Huai’an Hospital of Xuzhou Medical University, Huai’an 223002, Jiangsu Province, China
Min Xu, Department of Medical Imaging, The Affiliated Huai’an Hospital of Xuzhou Medical University, Huai’an 223002, Jiangsu Province, China
Yan-Song Ji, Health Management Center, The Affiliated Huai’an First People’s Hospital of Nanjing Medical University, Huai’an 223300, Jiangsu Province, China
Author contributions: Qian JJ performed most of the experiments and wrote the manuscript; Xu M designed the study and corrected the manuscript; Ji YS was involved in the analytical tools and participated in the collection of human material; all of the authors read and approved the final version of the manuscript to be published.
Institutional review board statement: This study was approved by the Affiliated Huai’an Hospital of Xuzhou Medical University, approval No. HEYLL202582.
Informed consent statement: All patients provided informed consent.
Conflict-of-interest statement: No benefits in any form have been received or will be received from any commercial party directly or indirectly related to the subject of this study.
Data sharing statement: The technical appendix, statistical code, and dataset are available from the corresponding author.
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Min Xu, Associate Chief Physician, Department of Medical Imaging, The Affiliated Huai’an Hospital of Xuzhou Medical University, No. 62 Huaihai South Road, Huai’an 223002, Jiangsu Province, China. xuminxum@163.com
Received: October 10, 2025
Revised: November 7, 2025
Accepted: November 28, 2025
Published online: January 27, 2026
Processing time: 103 Days and 1.5 Hours
Revised: November 7, 2025
Accepted: November 28, 2025
Published online: January 27, 2026
Processing time: 103 Days and 1.5 Hours
Core Tip
Core Tip: This study demonstrated the prognostic efficacy of combining contrast-enhanced ultrasound with Doppler ultrasound to predict postoperative outcomes in patients with hepatocellular carcinoma following transcatheter arterial chemoembolization (TACE). Patients with a favorable prognosis exhibited longer arterial transit and washout times, increased portal vein flow velocity, reduced peak systolic velocity in the hepatic artery, and lower blood flow grading than those with poor outcomes. The combination of these metrics demonstrates significant value in predicting prognosis fol