Retrospective Study
Copyright ©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Surg. Jun 27, 2025; 17(6): 103298
Published online Jun 27, 2025. doi: 10.4240/wjgs.v17.i6.103298
T2 magnetic resonance imaging combined with diffusion-weighted imaging for colon cancer lymph nodes
Yong-Xia Li, Sheng-Li Cai, Ming-Yang Peng, Tong-Xing Wang, Wen Geng, Yue-Hu Ma
Yong-Xia Li, Sheng-Li Cai, Department of Imaging, Nanjing Pukou District Hospital of Traditional Chinese Medicine, Nanjing 211800, Jiangsu Province, China
Ming-Yang Peng, Tong-Xing Wang, Wen Geng, Yue-Hu Ma, Department of Imaging, Nanjing First Hospital, Nanjing Medical University, Nanjing 210006, Jiangsu Province, China
Author contributions: Li YX designed the research study; Cai SL, Peng MY, Wang TX, Geng W, and Ma YH performed the research; Li XS and Ma YH analyzed the data and wrote the manuscript; All the authors read and approve the final manuscript.
Institutional review board statement: This study was reviewed and approved by the Institutional Review Committee of Nanjing Pukou District Hospital of Traditional Chinese Medicine (No. NJ901547).
Informed consent statement: All study participants or their legal guardian provided informed written consent about personal and medical data collection prior to study enrollment.
Conflict-of-interest statement: The authors declare that they have no conflict of interest.
Data sharing statement: No other available data.
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Yue-Hu Ma, MD, Chief Physician, Department of Imaging, Nanjing First Hospital, Nanjing Medical University, No. 68 Changle Road, Qinhuai District, Nanjing 210006, Jiangsu Province, China. mayuehu1976@163.com
Received: March 5, 2025
Revised: March 28, 2025
Accepted: April 29, 2025
Published online: June 27, 2025
Processing time: 86 Days and 4 Hours
Core Tip

Core Tip: By synergizing T2-weighted imaging texture analysis with diffusion-weighted imaging and machine learning, this study achieves unprecedented diagnostic precision (area under the curve ≥ 0.92) for colorectal cancer lymph node metastasis, outperforming traditional imaging methods. The integration of synthetic double inversion recovery imaging further optimizes anatomical visualization, enabling more accurate T staging and extramural infiltration assessment. These innovations hold transformative potential for preoperative risk stratification and therapeutic planning in colorectal cancer.