Min ZY, Zhou J, Zhu ZW, Fa ZZ. Efficacy of laparoscopic radical resection of colorectal cancer in older patients and its effects on inflammatory factors. World J Gastrointest Surg 2025; 17(5): 103065 [DOI: 10.4240/wjgs.v17.i5.103065]
Corresponding Author of This Article
Zhen-Zhong Fa, Department of General Surgery, Wujin Hospital Affiliated to Jiangsu University, No. 2 Yongning North Road, Changzhou 213004, Jiangsu Province, China. fazz9328423@yeah.net
Research Domain of This Article
Medicine, General & Internal
Article-Type of This Article
Retrospective Study
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Gastrointest Surg. May 27, 2025; 17(5): 103065 Published online May 27, 2025. doi: 10.4240/wjgs.v17.i5.103065
Efficacy of laparoscopic radical resection of colorectal cancer in older patients and its effects on inflammatory factors
Zhen-Yu Min, Jie Zhou, Zhong-Wei Zhu, Zhen-Zhong Fa
Zhen-Yu Min, Jie Zhou, Zhong-Wei Zhu, Zhen-Zhong Fa, Department of General Surgery, Wujin Hospital Affiliated to Jiangsu University, Changzhou 213004, Jiangsu Province, China
Author contributions: Min ZY contributed to manuscript writing, data collection, and analysis; Min ZY, Zhou J, Zhu ZW, and Fa ZZ collected the data; Min ZY and Fa ZZ were involved in the conceptualization and supervision of this manuscript; and all authors have approved the final manuscript.
Supported by the Medical Research Project of Jiangsu Health Commission, No. Z2021010.
Institutional review board statement: This study was approved by the Ethics Committee of Wujin Hospital Affiliated to Jiangsu University.
Informed consent statement: Patients were not required to give informed consent to the study because the analysis used anonymous clinical data that were obtained after each patient agreed to treatment by written consent.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Data sharing statement: No additional data are available.
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Zhen-Zhong Fa, Department of General Surgery, Wujin Hospital Affiliated to Jiangsu University, No. 2 Yongning North Road, Changzhou 213004, Jiangsu Province, China. fazz9328423@yeah.net
Received: February 7, 2025 Revised: February 27, 2025 Accepted: March 31, 2025 Published online: May 27, 2025 Processing time: 104 Days and 17.5 Hours
Core Tip
Core Tip: This study aimed to determine the clinical advantages of laparoscopic radical resection of colorectal cancer (LRRCC) in elderly patients across multiple dimensions, including therapeutic efficacy, postoperative complications, surgical outcomes, recovery, and inflammatory factors. A retrospective analysis was conducted on 104 elderly patients with colorectal cancer. The results revealed that LRRCC in elderly patients provides both higher efficacy and safety. Although LRRCC prolonged the operation time, it significantly reduced intraoperative blood loss, accelerated postoperative recovery, and effectively suppressed serum inflammatory factors in patients. These results indicate LRRCC as a safe and reliable surgical approach for elderly patients with colorectal cancer while providing valuable information for clinical surgical practice.
