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©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Surg. Apr 27, 2025; 17(4): 101439
Published online Apr 27, 2025. doi: 10.4240/wjgs.v17.i4.101439
Published online Apr 27, 2025. doi: 10.4240/wjgs.v17.i4.101439
Novel multimodal analgesic regimen for perioperative pain management after hepatic artery infusion chemotherapy in patients with advanced hepatocellular carcinoma
Jing Yan, Rui An, Jing-Jing Wang, Min Wang, Qi Zhao, Shen Zhao, Jian Xu, Department of Interventional Surgery Center, Xijing Hospital, The Fourth Military Medical University, Xi’an 710032, Shaanxi Province, China
Co-first authors: Jing Yan and Rui An.
Author contributions: Yan J and An R designed the research and wrote the first manuscript; Yan J, An R, Xu J, Wang JJ, Wang M, Zhao Q and Zhao S contributed to conceiving the research and analyzing data; Yan J and An R conducted the analysis and provided guidance for the research; all authors reviewed and approved the final manuscript. Yan J and An R contributed equally to this work as co-first authors.
Supported by Beijing Medical Award Foundation of China, No. YXJL-2023-0638-0048.
Institutional review board statement: This study was approved by the Medical Ethics Committee of Xijing Hospital, The Fourth Military Medical University.
Clinical trial registration statement: This study is registered at the Clinical Registry: https://www.chictr.org.cn/ (ChiCTR2300073724).
Informed consent statement: All patients involved in this study have provided written informed consent.
Conflict-of-interest statement: There is no conflict of interest.
CONSORT 2010 statement: The authors have read the CONSORT 2010 Statement, and the manuscript was prepared and revised according to the CONSORT 2010 Statement.
Data sharing statement: No additional data are available.
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Jian Xu, PhD, Department of Interventional Surgery Center, Xijing Hospital, The Fourth Military Medical University, No. 127 Changle West Road, Xi’an 710032, Shaanxi Province, China. xujian4327@163.com
Received: December 20, 2024
Revised: January 20, 2025
Accepted: February 27, 2025
Published online: April 27, 2025
Processing time: 98 Days and 23.2 Hours
Revised: January 20, 2025
Accepted: February 27, 2025
Published online: April 27, 2025
Processing time: 98 Days and 23.2 Hours
Core Tip
Core Tip: Multimodal analgesia is an approach that combines different analgesic medications and techniques to target multiple pain pathways, enhancing pain relief while minimizing adverse effects. This study investigates the effectiveness of a multimodal regimen in managing pain after hepatic artery infusion chemotherapy procedures.