Song JQ, Zhou T, Luo Y, Liu Y. Internal biliary diversion using appendix during liver transplantation for progressive familial intrahepatic cholestasis type 1: A case report. World J Gastrointest Surg 2025; 17(2): 101239 [DOI: 10.4240/wjgs.v17.i2.101239]
Corresponding Author of This Article
Yuan Liu, Assistant Professor, MD, Department of Liver Surgery, Renji Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, No. 160 Pujian Road, Shanghai 200127, China. liuyuanbird@163.com
Research Domain of This Article
Surgery
Article-Type of This Article
Case Report
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Gastrointest Surg. Feb 27, 2025; 17(2): 101239 Published online Feb 27, 2025. doi: 10.4240/wjgs.v17.i2.101239
Internal biliary diversion using appendix during liver transplantation for progressive familial intrahepatic cholestasis type 1: A case report
Jia-Qi Song, Tao Zhou, Yi Luo, Yuan Liu
Jia-Qi Song, Tao Zhou, Yi Luo, Yuan Liu, Department of Liver Surgery, Renji Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai 200127, China
Author contributions: Song JQ wrote the paper; Song JQ and Liu Y designed the study; Zhou T and Luo Y collected the data; Liu Y revised the paper and funded the study; and all authors thoroughly reviewed and endorsed the final manuscript.
Supported by the National Natural Science Foundation of China, No. 82471804.
Informed consent statement: This study obtained informed consent.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Yuan Liu, Assistant Professor, MD, Department of Liver Surgery, Renji Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, No. 160 Pujian Road, Shanghai 200127, China. liuyuanbird@163.com
Received: September 8, 2024 Revised: November 8, 2024 Accepted: December 17, 2024 Published online: February 27, 2025 Processing time: 135 Days and 18.3 Hours
Core Tip
Core Tip: Liver transplantation indicated in end-stage liver disease caused by progressive familial intrahepatic cholestasis type 1 is often performed with biliary diversion (BD). Although effectively preventing allograft steatosis, traditional BD increases post-operative infection risk. Here, we present a case of an 11-month-old progressive familial intrahepatic cholestasis type 1 patient receiving liver transplantation and BD using appendix to prevent post-operative infection. The proximal end and distal end of appendix were connected with intrahepatic biliary duct and colon respectively. Post-operative exams confirmed successful BD and absence of allograft steatosis. Thus, using appendix for BD might be a new surgical approach preventing allograft steatosis and post-transplant infection.
