©The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Surg. Sep 27, 2024; 16(9): 2925-2933
Published online Sep 27, 2024. doi: 10.4240/wjgs.v16.i9.2925
Published online Sep 27, 2024. doi: 10.4240/wjgs.v16.i9.2925
Impact of dexmedetomidine-assisted anesthesia in elderly patients undergoing radical resection of colon cancer
Xiao-Peng Tian, Hui-Min Bu, Hong-Yan Ma, Min Zhao, Department of Anesthesia Surgery, Qingdao University Affiliated Haici Hospital (Qingdao Hospital of Traditional Chinese Medicine), Qingdao 266033, Shandong Province, China
Co-first authors: Xiao-Peng Tian and Hui-Min Bu.
Author contributions: Tian XP and Bu HM were the guarantors and designed the study, and they contributed equally to this study as co-first authors; Zhao M, Bu HM and Tian XP participated in the acquisition, analysis, and interpretation of the data, and drafted the manuscript; Ma HY and Tian XP revised the article critically for important intellectual content.
Institutional review board statement: The study was reviewed and approved by the Science and Research Office of Qingdao University Affiliated Haici Hospital (Qingdao Hospital of Traditional Chinese Medicine).
Informed consent statement: All study participants, or their legal guardian, provided informed written consent prior to study enrollment.
Conflict-of-interest statement: There are no conflicts of interest to report.
Data sharing statement: No additional data are available.
Corresponding author: Min Zhao, Doctor, Department of Anesthesia Surgery, Qingdao University Affiliated Haici Hospital (Qingdao Hospital of Traditional Chinese Medicine), No. 4 Renmin Road, Shibei District, Qingdao 266033, Shandong Province, China.
Received: July 18, 2024
Revised: August 14, 2024
Accepted: August 16, 2024
Published online: September 27, 2024
Processing time: 62 Days and 3.2 Hours
Revised: August 14, 2024
Accepted: August 16, 2024
Published online: September 27, 2024
Processing time: 62 Days and 3.2 Hours
Core Tip
Core Tip: This study investigated the anesthetic effects of dexmedetomidine (Dex) during radical surgery in elderly patients with colon cancer under general anesthesia. The use of Dex as an adjunct to general anesthesia for radical surgery in elderly patients with colon cancer resulted in better effectiveness of anesthesia, less intraoperative hemodynamic fluctuations, reduced inflammatory response caused by surgery, better pulmonary compliance, lower airway resistance, and decreased incidence of anesthesia-induced delirium.