©The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Surg. Jul 27, 2024; 16(7): 2319-2328
Published online Jul 27, 2024. doi: 10.4240/wjgs.v16.i7.2319
Published online Jul 27, 2024. doi: 10.4240/wjgs.v16.i7.2319
Impact of frailty on postoperative outcomes after hepatectomy: A systematic review and meta-analysis
Yao-Jia Lv, Day Surgery Ward, Huzhou Central Hospital, The Affiliated Central Hospital of Huzhou University, Huzhou 313000, Zhejiang Province, China
Guang-Xing Xu, School of Basic Medical Sciences, Zhejiang Chinese Medical University, Hangzhou 310053, Zhejiang Province, China
Jia-Rong Lan, Department of Medicine, Huzhou Traditional Chinese Medicine Hospital Affiliated to Zhejiang Chinese Medical University, Huzhou 313000, Zhejiang Province, China
Author contributions: Lv YJ, Xu GX, and Lan JR conceived and designed the study, collected the data, and performed the analysis; Lv YJ and Xu GX wrote the paper; Lan JR edited the paper; all authors have read and approved the final manuscript.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
PRISMA 2009 Checklist statement: The authors have read the PRISMA 2009 Checklist, and the manuscript was prepared and revised according to the PRISMA 2009 Checklist.
Corresponding author: Jia-Rong Lan, MD, Doctor, Department of Medicine, Huzhou Traditional Chinese Medicine Hospital Affiliated to Zhejiang Chinese Medical University, No. 315 South Street, Huzhou 313000, Zhejiang Province, China. sdwaters@126.com
Received: February 24, 2024
Revised: April 28, 2024
Accepted: May 27, 2024
Published online: July 27, 2024
Processing time: 149 Days and 6.3 Hours
Revised: April 28, 2024
Accepted: May 27, 2024
Published online: July 27, 2024
Processing time: 149 Days and 6.3 Hours
Core Tip
Core Tip: This meta-analysis examined how frailty affects people undergoing liver surgery (hepatectomy). Findings from published studies were utilized to compare frail individuals to non-frail ones in terms of outcomes after hepatectomy. The findings show that frail individuals had higher mortality rates while in the hospital and within 30 d and 90 d after surgery, compared to non-frail individuals. Frail people also had lower long-term survival rates, experienced more complications, and had to stay in the hospital longer. These findings suggest that it is important to consider frailty when planning hepatectomy.