Retrospective Study
Copyright ©The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Surg. Jun 27, 2024; 16(6): 1670-1680
Published online Jun 27, 2024. doi: 10.4240/wjgs.v16.i6.1670
Prediction and analysis of albumin-bilirubin score combined with liver function index and carcinoembryonic antigen on liver metastasis of colorectal cancer
Zhan-Mei Wang, Shu-Ping Pan, Jing-Jing Zhang, Jun Zhou
Zhan-Mei Wang, Department of Medical Oncology, Qilu Hospital (Qingdao), Cheeloo College Medicine, Shandong University, Qingdao 266000, Shandong Province, China
Shu-Ping Pan, Department of Gastroenterology, Feicheng People’s Hospital, Feicheng 271600, Shandong Province, China
Jing-Jing Zhang, Department of Anus and Intestine Surgery, Xiangya Hospital of Central South University, Changsha 410008, Hunan Province, China
Jun Zhou, Department of Oncology, Qilu Hospital (Qingdao), Cheeloo College Medicine, Shandong University, Qingdao 266000, Shandong Province, China
Author contributions: Wang ZM wrote the manuscript; Pan SP and Zhang JJ collected the data; Zhou J guided the study; and all authors reviewed, edited, and approved the final manuscript and revised it critically for important intellectual content, gave final approval of the version to be published, and agreed to be accountable for all aspects of the work.
Institutional review board statement: This research was approved by the Ethics Committee of Xiangya Hospital of Central South University (Approval No. 2023A-402).
Informed consent statement: All study participants, or their legal guardian, provided informed written consent prior to study enrollment.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Data sharing statement: The technical appendix, statistical code, and dataset are available from the corresponding author at email: dr.zhouj@163.com.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Jun Zhou, Doctor, Department of Oncology, Qilu Hospital (Qingdao), Cheeloo College Medicine, Shandong University, No. 758 Hefei Road, Shibei District, Qingdao 266000, Shandong Province, China. dr.zhouj@163.com
Received: February 18, 2024
Revised: April 13, 2024
Accepted: April 26, 2024
Published online: June 27, 2024
Processing time: 132 Days and 17.2 Hours
Core Tip

Core Tip: This study investigated the application of the albumin bilirubin (ALBI) and liver function indices (aspartate aminotransferase, alanine aminotransferase, total bilirubin, etc.) combined with carcinoembryonic antigen (CEA) for the prediction of liver metastasis in patients with colorectal cancer (CRC). Through retrospective analysis of clinical data, we explored the associations of the ALBI and CEA level with liver metastasis in patients with CRC and established predictive models. The results of this study will provide clinicians with a simple and effective way to assess the risk of liver metastasis in patients with CRC and guide the development of treatment options that can help improve patient prognosis and survival.