Retrospective Study
Copyright ©The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Surg. Jun 27, 2024; 16(6): 1609-1617
Published online Jun 27, 2024. doi: 10.4240/wjgs.v16.i6.1609
Identifying the risk factors for pancreatic fistula after laparoscopic pancreaticoduodenectomy in patients with pancreatic cancer
Hang Xu, Qing-Cai Meng, Jie Hua, Wei Wang
Hang Xu, Qing-Cai Meng, Jie Hua, Wei Wang, Department of Pancreatic Surgery, Fudan University Shanghai Cancer Center, Shanghai 200032, China
Hang Xu, Qing-Cai Meng, Jie Hua, Wei Wang, Department of Oncology, Shanghai Medical College, Fudan University, Shanghai 200032, China
Author contributions: Xu H performed the research; Hua J contributed to the analysis; Wand W and Meng QC supervised the report.
Institutional review board statement: The study was reviewed and approved by the Ethics Committee of the Fudan University Shanghai Cancer Center (Approval No. 2008222-16).
Informed consent statement: All study participants or their legal guardians provided written informed consent for personal and medical data collection before study enrollment.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Data sharing statement: The raw data used in this study can be obtained from the corresponding author upon request.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Wei Wang, MD, Professor, Department of Pancreatic Surgery, Fudan University Shanghai Cancer Center, No. 270 Dong’an Road, Xuhui District, Shanghai 200032, China. wangwei@fudanpci.org
Received: February 20, 2024
Revised: April 11, 2024
Accepted: April 26, 2024
Published online: June 27, 2024
Processing time: 131 Days and 1.3 Hours
Core Tip

Core Tip: Controlling the highly correlated risk factors of pancreatic fistula (PF) following laparoscopic pancreaticoduodenectomy (LPD) can decrease PF incidence. Although existing studies have confirmed that the occurrence of PF after LPD is influenced by various factors, including self-development and surgery-related factors, few studies have examined the factors influencing the development of PF after LPD in pancreatic cancer. Here, we analyzed the factors associated with the development of PF after LPD for pancreatic cancer and found that body mass index (> 24.91 kg/m²), hypertension, soft pancreatic texture, and operation time (> 414 min) were risk factors.