Retrospective Study
Copyright ©The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Surg. May 27, 2024; 16(5): 1344-1353
Published online May 27, 2024. doi: 10.4240/wjgs.v16.i5.1344
Prognostic prediction model of colorectal cancer based on preoperative serum tumor markers
Yu-Hang Diao, Si-Qi Rao, Xin-Peng Shu, Yong Cheng, Can Tan, Li-Juan Wang, Dong Peng
Yu-Hang Diao, Si-Qi Rao, Xin-Peng Shu, Yong Cheng, Can Tan, Li-Juan Wang, Dong Peng, Department of Gastrointestinal Surgery, The First Affiliated Hospital of Chongqing Medical University, Chongqing 400016, China
Co-first authors: Yu-Hang Diao and Si-Qi Rao.
Author contributions: Rao SQ was thanked for her significant contribution in revising the manuscript; Diao YH and Rao SQ contributed to the data analysis; Peng D led the quality assessments, Diao YH wrote the original draft; Shu XP and Cheng Y revised the manuscript. All authors have agreed on the manuscript to be submitted, provided final approval of the version to be published, and agree to be responsible for all elements of the work. Diao YH and Rao SQ contributed equally to this work.
Supported by CQMU Program for Youth Innovation in Future Medicine, No. W0190.
Institutional review board statement: This study was reviewed and approved by the Ethics Committee of The First Affiliated Hospital of Chongqing Medical University.
Informed consent statement: This study is a retrospective study, and the patients is come from a teaching hospital of the First Affiliated Hospital of Chongqing Medical University. When we deliver the ethics application, we have also delivered application for exemption of informed consent, and This study was approved by the Medical Ethics Committee of the First Affiliated Hospital of Chongqing Medical University (2022-133-2).
Conflict-of-interest statement: The authors declare no conflicts of interest.
Data sharing statement: The datasets generated and/or analyzed during the current study are not publicly available due but are available from the corresponding author upon reasonable request.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/licenses/by-nc/4.0/
Corresponding author: Dong Peng, PhD, Chief Doctor, Department of Gastrointestinal Surgery, The First Affiliated Hospital of Chongqing Medical University, No. 1 Youyi Road, Yuzhong District, Chongqing 400016, China. carry_dong@126.com
Received: January 28, 2024
Revised: April 6, 2024
Accepted: April 15, 2024
Published online: May 27, 2024
Processing time: 116 Days and 3.5 Hours
Core Tip

Core Tip: The tumor markers carcinoembryonic antigen and carbohydrate antigen 19-9 are often used in the auxiliary diagnosis and postoperative monitoring of colorectal patients, but their role in prognosis needs to be further explored. Here, we retrospectively analyzed the clinical data and pathological characteristics of 3526 patients with nonmetastatic colorectal cancer (CRC), confirmed the negative correlation between preoperative serum tumor marker levels and prognosis, and established a nomogram model to evaluate the prognosis of CRC patients.