Copyright
©The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Surg. Mar 27, 2024; 16(3): 823-832
Published online Mar 27, 2024. doi: 10.4240/wjgs.v16.i3.823
Published online Mar 27, 2024. doi: 10.4240/wjgs.v16.i3.823
Reinforced tissue matrix to strengthen the abdominal wall following reversal of temporary ostomies or to treat incisional hernias
Spencer P Lake, Mechanical Engineering & Materials Science, Washington University in St. Louis, St. Louis, MO 63130, United States
Corey R Deeken, Covalent Bio, LLC, St. Louis, MO 63025, United States
Amit K Agarwal, Department of Surgery, McGovern Medical School at UTHealth, Houston, TX 77026, United States
Author contributions: Agarwal AK designed the study; Agarwal AK performed the research; Agarwal AK, Lake SP, and Deeken CR analyzed the data and wrote the manuscript; and all authors have read and approve the final manuscript.
Institutional review board statement: This study was reviewed and approved by the UT Health Houston Institutional Review Board (approval No. HSC-MS-23-0471).
Informed consent statement: All study participants, or their legal guardian, provided consent prior to study enrollment.
Conflict-of-interest statement: This project was sponsored by TELA Bio of Malvern, PA (USA). Dr. Deeken is the owner of Covalent Bio, LLC, which received consulting fees from TELA Bio for this project, as well as other unrelated projects. Dr. Deeken also reports consulting fees from C.R. Bard, Inc./Davol/Becton, Dickinson and Company, Johnson & Johnson, Medtronic, SurgiMatrix, Tissium, Surgical Innovation Associates, Americas Hernia Society Quality Collaborative, Colorado Therapeutics, TELA Bio, Osteogenics, Polynovo, MedSkin Solutions, and Aran Biomedical outside the submitted work. In addition, Dr. Deeken holds the following issued patents: 2009293001, 2334257, 2,334,257UK, 602009046407.8, 2,334,257FR, 16/043,849 and 2,737,542. Dr. Lake is a consultant for Covalent Bio LLC and has received consulting fees from TELA Bio for the conduct of this study, as well as outside of the current work. Dr. Agarwal is a paid consultant for TELA Bio.
Data sharing statement: Dataset available from the corresponding author.
STROBE statement: The authors have read the STROBE Statement—checklist of items, and the manuscript was prepared and revised according to the STROBE Statement—checklist of items.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Amit K Agarwal, FACS, FASCRS, MD, Associate Professor, De
Received: October 27, 2023
Peer-review started: October 27, 2023
First decision: December 6, 2023
Revised: January 3, 2024
Accepted: February 25, 2024
Article in press: February 25, 2024
Published online: March 27, 2024
Processing time: 146 Days and 24 Hours
Peer-review started: October 27, 2023
First decision: December 6, 2023
Revised: January 3, 2024
Accepted: February 25, 2024
Article in press: February 25, 2024
Published online: March 27, 2024
Processing time: 146 Days and 24 Hours
Core Tip
Core Tip: Reinforced tissue matrices (RTMs), which include elements of both synthetic and biologic mesh materials, were shown to be effective in treating parastomal and incisional hernia following ileostomy or colostomy reversal. Twenty-eight patients received OviTex® RTM to reinforce the abdominal wall using a laparoscopic, robotic, or open surgical approach. Positive primary outcomes (i.e., 0% hernia recurrence) and low rates of complications were observed at 1-month and 1-year follow-up.