Retrospective Study
Copyright ©The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Surg. Mar 27, 2024; 16(3): 751-758
Published online Mar 27, 2024. doi: 10.4240/wjgs.v16.i3.751
Clinical study on the relationship between liver cirrhosis, ascites, and hyponatremia
Xuan-Ji Li, Hui-Hui Meng
Xuan-Ji Li, Department of Gastroenterology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, Hubei Province, China
Hui-Hui Meng, Department of Hepatology, Hubei Provincial Hospital of Traditional Chinese Medicine, Wuhan 430065, Hubei Province, China
Co-first authors: Xuan-Ji Li and Hui-Hui Meng.
Author contributions: Li XJ and Meng HH designed the study, collected and analyzed the clinical data and wrote the paper, contributed equally to this work as co-first authors; and both authors approved the final version of the manuscript.
Institutional review board statement: This study protocol was approved by Hubei Provincial Hospital of Traditional Chinese Medicine.
Informed consent statement: All the families have voluntarily participated in the study and have signed informed consent forms.
Conflict-of-interest statement: The authors declared no conflict of interest existing in this paper.
Data sharing statement: Data generated in this study can be obtained from the corresponding author.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Hui-Hui Meng, MM, Nurse, Department of Hepatology, Hubei Provincial Hospital of Traditional Chinese Medicine, No. 4 Huayuanshan, Wuchang District, Wuhan 430065, Hubei Province, China. lixuanji814@163.com
Received: December 22, 2023
Peer-review started: December 22, 2023
First decision: January 9, 2024
Revised: January 12, 2024
Accepted: January 31, 2024
Article in press: January 31, 2024
Published online: March 27, 2024
Processing time: 91 Days and 9.5 Hours
Core Tip

Core Tip: This study found that ascites combined with hyponatremia is a high-risk condition in patients with cirrhosis, which is characterized by older patients, an increased proportion of males, and prolonged hospitalization. Hyponatremia is more pronounced in this setting, with an increase in hepatic encephalopathy, renal impairment, and infection. Diuretics and salt supplements are preferred in treatment options. The poor prognosis of patients with ascites and hyponatremia prompts more attention to this patient in clinical practice and the adoption of timely and effective treatment measures, especially risk management for elderly and male patients.