Retrospective Study
Copyright ©The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Surg. Oct 27, 2024; 16(10): 3185-3201
Published online Oct 27, 2024. doi: 10.4240/wjgs.v16.i10.3185
Recurrence scoring system predicting early recurrence for patients with pancreatic ductal adenocarcinoma undergoing pancreatectomy and portomesenteric vein resection
Hang He, Cai-Feng Zou, Yong-Jian Jiang, Feng Yang, Yang Di, Ji Li, Chen Jin, De-Liang Fu
Hang He, Cai-Feng Zou, Yong-Jian Jiang, Feng Yang, Yang Di, Ji Li, Chen Jin, De-Liang Fu, Department of Pancreatic Surgery, Huashan Hospital, Shanghai Medical College, Fudan University, Shanghai 200040, China
Co-first authors: Hang He and Cai-Feng Zou.
Author contributions: He H and Zou CF contributed equally to the study; He H concepted and designed the research; Li J, Jin C and Fu DL provided administrative support; Jiang YJ, Yang F and Di Y contributed to follow-up; He H and Zou CF collected and assembled data; He H performed data analysis and wrote the manuscript; All authors read and approved the manuscript.
Supported by National Natural Science Foundation of China, No. 82373012.
Institutional review board statement: This study was reviewed and approved by the Clinical Research Ethics Committee of Huashan Hospital (Approval No. 1037).
Informed consent statement: This study retrospectively included data without any intervention for the patients. The informed consent document is not applicated.
Conflict-of-interest statement: The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
Data sharing statement: All data and results of this study were presented in the article and the supplementary file. No additional data are available.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/licenses/by-nc/4.0/
Corresponding author: Hang He, MD, PhD, Surgeon, Department of Pancreatic Surgery, Huashan Hospital, Shanghai Medical College, Fudan University, No. 12 Middle Wulumuqi Road, Shanghai 200040, China. hhe10@fudan.edu.cn
Received: May 26, 2024
Revised: August 19, 2024
Accepted: September 9, 2024
Published online: October 27, 2024
Processing time: 125 Days and 1.7 Hours
Core Tip

Core Tip: Portomesenteric vein involvement is common in pancreatic ductal adenocarcinoma, which is correlated to the poor outcome, and needs individualized therapy. Pancreatectomy and portomesenteric vein resection (PVR) allow patients to achieve radical resection, however, early recurrence is frequently observed. This study constructed the first tailored recurrence scoring system unique for patients undergoing pancreatectomy and PVR, which consisted of Serum Recurrence Score and Recurrence Nomogram. With this scoring system, clinicians could predict early recurrence efficiently, and identify patients at high-risk of recurrence for individualized therapy timely, aiming to restrain the recurrence and improve the prognosis.