Systematic Reviews
Copyright ©The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Surg. Aug 27, 2023; 15(8): 1799-1807
Published online Aug 27, 2023. doi: 10.4240/wjgs.v15.i8.1799
Intraoperative pancreas stump perfusion assessment during pancreaticoduodenectomy: A systematic scoping review
Francis P Robertson, Harry V M Spiers, Wei Boon Lim, Benjamin Loveday, Keith Roberts, Sanjay Pandanaboyana
Francis P Robertson, Wei Boon Lim, Sanjay Pandanaboyana, Department of HPB and Transplant Surgery, Freeman Hospital, Newcastle Upon Tyne NE7 7DN, United Kingdom
Harry V M Spiers, Department of HPB Surgery, Addenbrookes Hospital, Cambridge CB2 0QQ, United Kingdom
Benjamin Loveday, Department of General Surgery, Royal Melbourne Hospital, Melbourne VIC 3050, Australia
Keith Roberts, Department of HPB Surgery, University Hospitals Birmingham NHS Foundation Trust, Birmingham BG15 2GW, United Kingdom
Author contributions: Robertson FP, Spiers HVM, and Pandanaboyana S contributed to the manuscript preparation, study concept, and critical review; Loveday B and Roberts K were involved in the study concept and critical review.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
PRISMA 2009 Checklist statement: The authors have read the PRISMA 2009 Checklist, and the manuscript was prepared and revised according to the PRISMA 2009 Checklist.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Francis P Robertson, BSc, FRCS (Ed), MBChB, PhD, Surgeon, Department of HPB and Transplant Surgery, Freeman Hospital, Freeman Road, Newcastle Upon Tyne NE7 7DN, United Kingdom. francis.robertson.13@ucl.ac.uk
Received: April 13, 2023
Peer-review started: April 13, 2023
First decision: May 19, 2023
Revised: May 23, 2023
Accepted: June 11, 2023
Article in press: June 11, 2023
Published online: August 27, 2023
Processing time: 133 Days and 12.4 Hours
Core Tip

Core Tip: The pathology of post-op pancreatic fistula remains to be elucidated, however, hypoperfusion of the pancreatic remanent is a suggested mechanism leading to post-operative pancreatitis and failure of the pancreatic jejunal anastomosis. Indocyanine green assessment of the pancreatic remanent is a safe way to visualise perfusion of the stump prior to anastomosis. Whether it can predict post-operative pancreatic fistula requires further studies.