Retrospective Study
Copyright ©The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Surg. Aug 27, 2023; 15(8): 1684-1692
Published online Aug 27, 2023. doi: 10.4240/wjgs.v15.i8.1684
Clinical efficacy of total laparoscopic splenectomy for portal hypertension and its influence on hepatic hemodynamics and liver function
Rui-Zhao Qi, Zhi-Wei Li, Zheng-Yao Chang, Wei-Hua Chang, Wen-Lei Zhao, Chuan Pang, Ying Zhang, Xing-Long Hu, Feng Liang
Rui-Zhao Qi, Zheng-Yao Chang, Wei-Hua Chang, Wen-Lei Zhao, Chuan Pang, Ying Zhang, Xing-Long Hu, Feng Liang, Department of General Surgery, 5th Medical Center, Chinese PLA General Hospital, Beijing 100039, China
Zhi-Wei Li, Department of Hepatobiliary, The 3rd People’s Hospital of Shenzhen, Shenzhen 518112, Guangdong Province, China
Author contributions: Qi RZ and Li ZW contributed equally to this work and are co-first authors; Qi RZ and Li ZW contributed to the research design and thesis writing; Chang ZY, Liang F and Chang WH collected and analyzed the data; Qi RZ, Li ZW, Zhao WL and Pang YZ contributed to the data collection; Liang F overall supervise the study; all authors contributed to the article and approved the submitted version.
Institutional review board statement: The study was reviewed and approved by the Chinese PLA General Hospital Institutional Review Board (Approval No. 2010068D).
Informed consent statement: Patients were not required to give informed consent to the study because the analysis used anonymous clinical data that were obtained after each patient agreed to treatment by written consent.
Conflict-of-interest statement: There is no conflict of interest.
Data sharing statement: No additional data are available.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Feng Liang, PhD, Doctor, Department of General Surgery, 5th Medical Center, Chinese PLA General Hospital, No. 8 Dongdajie, Fengtai District, Beijing 100039, China. lfpeakcool@126.com
Received: April 6, 2023
Peer-review started: April 6, 2023
First decision: April 19, 2023
Revised: May 16, 2023
Accepted: June 6, 2023
Article in press: June 6, 2023
Published online: August 27, 2023
Processing time: 141 Days and 2.9 Hours
Core Tip

Core Tip: Portal hypertension (PH) can bring adverse effects to patients such as hepatic hemodynamic changes and decreased liver function. We propose and demonstrate that total laparoscopic splenectomy, although comparable to open splenectomy in clinical efficacy, safety, and effects on hepatic hemodynamics and liver function in patients with PH, has the advantage of less intraoperative blood loss.