Retrospective Study
Copyright ©The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Surg. Feb 27, 2023; 15(2): 211-221
Published online Feb 27, 2023. doi: 10.4240/wjgs.v15.i2.211
Prognostic value of preoperative immune-nutritional scoring systems in remnant gastric cancer patients undergoing surgery
Yan Zhang, Lin-Jun Wang, Qin-Ya Li, Zhen Yuan, Dian-Cai Zhang, Hao Xu, Li Yang, Xin-Hua Gu, Ze-Kuan Xu
Yan Zhang, Zhen Yuan, Xin-Hua Gu, Department of Gastrointestinal Surgery, Suzhou Municipal Hospital, Affiliated Suzhou Hospital of Nanjing Medical University, Gusu School of Nanjing Medical University, Suzhou 215000, Jiangsu Province, China
Lin-Jun Wang, Qin-Ya Li, Dian-Cai Zhang, Hao Xu, Li Yang, Ze-Kuan Xu, Department of General Surgery, Jiangsu Province Hospital, First Affiliated Hospital of Nanjing Medical University, Nanjing 210003, Jiangsu Province, China
Author contributions: Zhang Y, Wang LJ, and Xu ZK contributed equally to this work; Gu XH and Xu ZK designed the research study; Zhang Y and Wang LJ performed the research; Li QY contributed analytic tools; Yuan Z, Zhang DC, Xu H, and Yang L analyzed the data and wrote the manuscript; all authors have read and approved the final manuscript.
Supported by National Natural Science Foundation of China, No. 81871946 and No. 82072708; Suzhou Medical Key Discipline, No. SZXK202109; Suzhou Clinical Key Diseases Project, No. LCZX202111; Project of Gusu School of Nanjing Medical University, No. GSKY20210233.
Institutional review board statement: This study was approved by the medical ethics committee of Nanjing Medical University.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Data sharing statement: No additional data are available.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Xin-Hua Gu, Doctor, Department of Gastrointestinal Surgery, Suzhou Municipal Hospital, Affiliated Suzhou Hospital of Nanjing Medical University, Gusu School of Nanjing Medical University, No. 26 Daoqianjie, Gusu District, Suzhou 215000, Jiangsu Province, China. 1173421755@qq.com
Received: September 15, 2022
Peer-review started: September 15, 2022
First decision: December 12, 2022
Revised: December 14, 2022
Accepted: December 31, 2022
Article in press: December 31, 2022
Published online: February 27, 2023
Processing time: 164 Days and 19.9 Hours
Core Tip

Core Tip: Three preoperative immune-nutritional scores of patients with remnant gastric cancer (RGC) were calculated, including prognostic nutritional index (PNI), controlled nutritional status (CONUT), and Naples prognostic score (NPS). Patients were divided into groups according to the immune-nutritional risk. The three immune-nutritional scoring systems were significantly correlated with overall survival (OS) (PNI: P = 0.002; CONUT: P = 0.039; NPS: P < 0.001). Survival analysis revealed a significant difference in OS between different immune-nutritional groups (PNI: 75 mo vs 42 mo, P = 0.001; CONUT: 69 mo vs 48 mo, P = 0.033; NPS: 77 mo vs 40 mo, P < 0.001). These preoperative immune-nutritional scores are reliable multidimensional RGC prognostic scoring systems.