Retrospective Study
Copyright ©The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Surg. Nov 27, 2023; 15(11): 2456-2462
Published online Nov 27, 2023. doi: 10.4240/wjgs.v15.i11.2456
Correlation between pre-treatment serum total blood bilirubin and unconjugated bilirubin and prognosis in patients with colorectal cancer
Hui Tong, Peng Xing, Zhao-Ning Ji
Hui Tong, Peng Xing, Department of Medicine Oncology, Anhui Jingxian Hospital, Xuancheng 242500, Anhui Province, China
Zhao-Ning Ji, Department of Medicine Oncology, The First Affiliated Hospital of Wannan Medical College-Yijishan Hospital, Wuhu 241000, Anhui Province, China
Author contributions: Ji ZN designed the research; Tong H performed the research; Ji ZN and Xing P contributed new reagents or analytic tools; Tong H analyzed data and wrote the paper.
Institutional review board statement: This study was reviewed and approved by the Ethics Committee of Jingxian Hospital in Anhui Province.
Informed consent statement: As the study used anonymous and pre-existing data, the requirement for informed consent from patients was waived.
Conflict-of-interest statement: We have no financial relationships to disclose.
Data sharing statement: No additional data are available.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Zhao-Ning Ji, Doctor, MD, Chief Doctor, Department of Medicine Oncology, The First Affiliated Hospital of Wannan Medical College-Yijishan Hospital, No. 2 Zheshan West Road, Wuhu 241000, Anhui Province, China. jzn18963705636@163.com
Received: August 9, 2023
Peer-review started: August 9, 2023
First decision: August 24, 2023
Revised: August 29, 2023
Accepted: September 20, 2023
Article in press: September 20, 2023
Published online: November 27, 2023
Processing time: 110 Days and 1.2 Hours
Core Tip

Core Tip: In this study, we demonstrated that bilirubin levels may be used as a prognostic indicator in colorectal cancer (CRC) patients. Higher total bilirubin (TBIL) and unconjugated bilirubin levels were negatively correlated with 3-year survival in CRC patients. TBIL may be used as a protective prognostic indicator in patients with CRC.