©The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Surg. Nov 27, 2023; 15(11): 2456-2462
Published online Nov 27, 2023. doi: 10.4240/wjgs.v15.i11.2456
Published online Nov 27, 2023. doi: 10.4240/wjgs.v15.i11.2456
Correlation between pre-treatment serum total blood bilirubin and unconjugated bilirubin and prognosis in patients with colorectal cancer
Hui Tong, Peng Xing, Department of Medicine Oncology, Anhui Jingxian Hospital, Xuancheng 242500, Anhui Province, China
Zhao-Ning Ji, Department of Medicine Oncology, The First Affiliated Hospital of Wannan Medical College-Yijishan Hospital, Wuhu 241000, Anhui Province, China
Author contributions: Ji ZN designed the research; Tong H performed the research; Ji ZN and Xing P contributed new reagents or analytic tools; Tong H analyzed data and wrote the paper.
Institutional review board statement: This study was reviewed and approved by the Ethics Committee of Jingxian Hospital in Anhui Province.
Informed consent statement: As the study used anonymous and pre-existing data, the requirement for informed consent from patients was waived.
Conflict-of-interest statement: We have no financial relationships to disclose.
Data sharing statement: No additional data are available.
Corresponding author: Zhao-Ning Ji, Doctor, MD, Chief Doctor, Department of Medicine Oncology, The First Affiliated Hospital of Wannan Medical College-Yijishan Hospital, No. 2 Zheshan West Road, Wuhu 241000, Anhui Province, China. jzn18963705636@163.com
Received: August 9, 2023
Peer-review started: August 9, 2023
First decision: August 24, 2023
Revised: August 29, 2023
Accepted: September 20, 2023
Article in press: September 20, 2023
Published online: November 27, 2023
Processing time: 110 Days and 1.2 Hours
Peer-review started: August 9, 2023
First decision: August 24, 2023
Revised: August 29, 2023
Accepted: September 20, 2023
Article in press: September 20, 2023
Published online: November 27, 2023
Processing time: 110 Days and 1.2 Hours
Core Tip
Core Tip: In this study, we demonstrated that bilirubin levels may be used as a prognostic indicator in colorectal cancer (CRC) patients. Higher total bilirubin (TBIL) and unconjugated bilirubin levels were negatively correlated with 3-year survival in CRC patients. TBIL may be used as a protective prognostic indicator in patients with CRC.