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©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Surg. Jul 27, 2022; 14(7): 727-730
Published online Jul 27, 2022. doi: 10.4240/wjgs.v14.i7.727
Published online Jul 27, 2022. doi: 10.4240/wjgs.v14.i7.727
Signs and syndromes in acute appendicitis: A pathophysiologic approach
Steven Howard Yale, Internal Medicine, University of Central Florida, Orlando, FL 32827, United States
Halil Tekiner, Department of the History of Medicine and Ethics, Erciyes University School of Medicine, Melikgazi 38039, Kayseri, Turkey
Eileen Scott Yale, Division of General Internal Medicine, University of Florida, Gainesville, FL 32608, United States
Author contributions: Yale SH, Tekiner H, and Yale ES wrote the manuscript; all authors have read and approved the final manuscript.
Conflict-of-interest statement: The authors declare no conflict of interest for this article.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Steven Howard Yale, MD, Professor, Internal Medicine, University of Central Florida, 6850 Lake Nona Blvd, Orlando, FL 32827, United States.
Received: February 12, 2022
Peer-review started: February 12, 2022
First decision: April 19, 2022
Revised: April 20, 2022
Accepted: July 5, 2022
Article in press: July 5, 2022
Published online: July 27, 2022
Processing time: 164 Days and 22 Hours
Peer-review started: February 12, 2022
First decision: April 19, 2022
Revised: April 20, 2022
Accepted: July 5, 2022
Article in press: July 5, 2022
Published online: July 27, 2022
Processing time: 164 Days and 22 Hours
Core Tip
Core Tip: This paper describes the pathophysiologic mechanism of disease presentation and reports the signs of acute appendicitis as initially reported. Physical examination signs and syndromes have not been well studied in patients with acute appendicitis. Knowledge of how to appropriately perform these bedside maneuvers in diagnosing appendicitis may provide further knowledge about the likelihood of the disease. Understanding the mechanism of disease and these bedside maneuvers may further enhance the ability of surgeons to diagnose acute appendicitis.