©The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Surg. Oct 27, 2021; 13(10): 1216-1225
Published online Oct 27, 2021. doi: 10.4240/wjgs.v13.i10.1216
Published online Oct 27, 2021. doi: 10.4240/wjgs.v13.i10.1216
Utility of preoperative systemic inflammatory biomarkers in predicting postoperative complications after pancreaticoduodenectomy: Literature review and single center experience
Alessandro Coppola, Department of Surgery, University Campus Bio-Medico di Roma, Rome 00128, Italy
Vincenzo La Vaccara, Lorenza Caggiati, Ludovico Carbone, Roberto Coppola, Damiano Caputo, Department of General Surgery, University Campus Bio-Medico di Roma, Rome 00128, Italy
Silvia Spoto, Department of Internal Medicine, University Campus Bio-Medico di Roma, Rome 00128, Italy
Massimo Ciccozzi, Medical Statistics and Epidemiology Unit, University Campus Bio-Medico di Roma, Rome 00128, Italy
Silvia Angeletti, Unit of Clinical Laboratory Science, University Campus Bio-Medico di Roma, Rome 00128, Italy
Author contributions: Caputo D and Coppola A designed the research study; Caggiati L and Ludovico C collected the data; Caputo D, Ciccozzi M, Angeletti S and Spoto S analyzed and interpreted data; Caputo D, Coppola A and Caggiati L drafted the article; Caputo D, Spoto S, Angeletti S and Coppola R made critical revision of the article; All the authors gave the final approval of the version to be published.
Institutional review board statement: The local Ethical Committee approved the study (28/19 OSS ComEt CBM).
Informed consent statement: Patients were not required to give informed consent to the study because the analysis used anonymous clinical data that were obtained after each patient agreed to treatment by written consent.
Conflict-of-interest statement: All authors declare that they do not have any conflict of interest.
Data sharing statement: Dataset will be available from the corresponding author at d.caputo@unicampus.it according to local laws.
Corresponding author: Damiano Caputo, FACS, MD, Associate Professor, Surgeon, Department of General Surgery, University Campus Bio-Medico di Roma, Via Alvaro del Portillo, 200, Rome 00128, Italy. d.caputo@unicampus.it
Received: January 25, 2021
Peer-review started: January 25, 2021
First decision: May 3, 2021
Revised: May 10, 2021
Accepted: July 13, 2021
Article in press: July 13, 2021
Published online: October 27, 2021
Processing time: 273 Days and 21 Hours
Peer-review started: January 25, 2021
First decision: May 3, 2021
Revised: May 10, 2021
Accepted: July 13, 2021
Article in press: July 13, 2021
Published online: October 27, 2021
Processing time: 273 Days and 21 Hours
Core Tip
Core Tip: Inflammatory markers are involved in cancer’s pathogenesis and growth. In addition, their role in predicting post-operative complications in colorectal and otorhinolaryngeal surgery has been reported. Here, the role of preoperative inflammatory biomarkers in predicting postoperative complication after pancreaticoduodenectomy has been investigated.