Chen JH, Zhang MF, Du WC, Zhang YA. Risk factors and their interactive effects on severe acute pancreatitis complicated with acute gastrointestinal injury. World J Gastrointest Surg 2023; 15(8): 1712-1718 [PMID: 37701702 DOI: 10.4240/wjgs.v15.i8.1712]
Corresponding Author of This Article
Yan-An Zhang, MBBS, Professor, Emergency Department, Longyan First Affiliated Hospital of Fujian Medical University, No. 105 Jiuyibei Road, Xinluo District, Longyan 364000, Fujian Province, China. zhangyanan6870@163.com
Research Domain of This Article
Emergency Medicine
Article-Type of This Article
Retrospective Study
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Gastrointest Surg. Aug 27, 2023; 15(8): 1712-1718 Published online Aug 27, 2023. doi: 10.4240/wjgs.v15.i8.1712
Risk factors and their interactive effects on severe acute pancreatitis complicated with acute gastrointestinal injury
Jian-Hui Chen, Mei-Fen Zhang, Wen-Chao Du, Yan-An Zhang
Jian-Hui Chen, Mei-Fen Zhang, Wen-Chao Du, Yan-An Zhang, Emergency Department, Longyan First Affiliated Hospital of Fujian Medical University, Longyan 364000, Fujian Province, China
Author contributions: Chen JH designed and performed the research and wrote the paper; Zhang YA designed the research and supervised the report; Zhang MF designed the research and contributed to the analysis; Du WC supervised the report.
Institutional review board statement: This study was approved by the Medical Ethics Committee of Longyan First Affiliated Hospital of Fujian Medical University (Approved No. LYREC2023-k016-01).
Informed consent statement: This was a retrospective study and was exempt from informed consent according to Institutional policy.
Conflict-of-interest statement: The authors declare no conflicts of interest for this article.
Data sharing statement: The data used for this study can be obtained from the corresponding author upon request.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Yan-An Zhang, MBBS, Professor, Emergency Department, Longyan First Affiliated Hospital of Fujian Medical University, No. 105 Jiuyibei Road, Xinluo District, Longyan 364000, Fujian Province, China. zhangyanan6870@163.com
Received: May 6, 2023 Peer-review started: May 6, 2023 First decision: May 19, 2023 Revised: May 26, 2023 Accepted: June 21, 2023 Article in press: June 21, 2023 Published online: August 27, 2023 Processing time: 111 Days and 8 Hours
ARTICLE HIGHLIGHTS
Research background
Acute gastrointestinal injury (AGI) patients are prone to gastrointestinal dysfunction and mucosal injury, aggravating the degree of pancreatic inflammation and causing multiple organ dysfunction.
Research motivation
Examining the risk factors of AGI is of great significance for controlling the development of AGI and improving the prognosis of severe acute pancreatitis (SAP).
Research objectives
The purpose of this study was to analyze the risk factors of SAP complicated by AGI and their interaction.
Research methods
This study retrospectively analyzed SAP patients admitted to our hospital and divided them into the AGI group and non-AGI group to analyze the risk factors of SAP complicated with AGI and their interaction.
Research results
An acute physiological and chronic health scoring system II score > 15 and creatinine level > 100 μmol/L were independent risk factors for SAP complicated with AGI, and there was a positive interaction between them.
Research conclusions
When risk factors of SAP complicated with AGI are found, timely effective measures should be taken to improve the prognosis of SAP patients.
Research perspectives
In SAP patients with AGI, attention should be paid to managing the risk factors of AGI in SAP patients, and timely and effective interventions should be carried out to reduce the incidence of AGI and to improve the prognosis of SAP patients.
