Bhambare MR, Pandya JS, Waghmare SB, Shetty TS. Gastrointestinal stromal tumour presenting as palpable abdominal mass: A rare entity. World J Gastrointest Surg 2015; 7(6): 98-101 [PMID: 26131332 DOI: 10.4240/wjgs.v7.i6.98]
Corresponding Author of This Article
Dr. Jayashri S Pandya, Professor, Department of General Surgery, Topiwala National Medical College and Bai Yamunabai Laxman Nair Hospital, Mumbai Central, Mumbai 400008, India. smruti63@hotmail.com
Research Domain of This Article
Surgery
Article-Type of This Article
Case Report
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Gastrointest Surg. Jun 27, 2015; 7(6): 98-101 Published online Jun 27, 2015. doi: 10.4240/wjgs.v7.i6.98
Gastrointestinal stromal tumour presenting as palpable abdominal mass: A rare entity
Manoj R Bhambare, Jayashri S Pandya, Sudatta B Waghmare, Tilakdas S Shetty
Manoj R Bhambare, Jayashri S Pandya, Sudatta B Waghmare, Tilakdas S Shetty, Department of General Surgery, Topiwala National Medical College and Bai Yamunabai Laxman Nair Hospital, Mumbai 400008, India
Author contributions: All authors contributed to this manuscript.
Ethics approval: The study reviewed and waivered by the BYL Nair Hospital and T N Medical College ethics committee.
Informed consent: The study participant provided informed written consent.
Conflict-of-interest: We certify that there is no conflict of interest with any financial organisation regarding material discussed in the manuscript.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Dr. Jayashri S Pandya, Professor, Department of General Surgery, Topiwala National Medical College and Bai Yamunabai Laxman Nair Hospital, Mumbai Central, Mumbai 400008, India. smruti63@hotmail.com
Telephone: +91-02-223027148
Received: December 3, 2014 Peer-review started: December 7, 2014 First decision: February 7, 2015 Revised: April 16, 2015 Accepted: May 5, 2015 Article in press: May 6, 2015 Published online: June 27, 2015 Processing time: 299 Days and 12.6 Hours
Abstract
Gastrointestinal stromal tumours (GISTs) are the most common mesenchymal tumour of gastro-intestinal tract. Annual incidence of GIST in United States is approximately 3000-4000. Clinical presentation of GIST varies with location and size of tumour but GIST presenting with palpable abdominal mass is rare. We report a case of 38 years old male who presented with large abdominal lump. Computed tomography (CT) scan showed a large solid-cystic lesion encasing second part of duodenum and distal common bile duct. On CT differential diagnosis of Leiomyoma, Leiomyosarcoma and GIST were made. The diagnosis of GIST was confirmed by immune-histochemical study of the biopsy material. Patient underwent pancreaticodudenectomy. Post-operative course was uneventful. Patient was started on Imatinib therapy post-operatively. No recurrence noted at six months follow up.
Core tip: Gastrointestinal stromal tumours presenting with palpable abdominal mass are rare. Diagnosis is based upon histopathology and immunehistochemistry. Pre operatively patient should be evaluated with different modalities for diagnosis and resectability of tumour. Surgical resection with postoperative Imatinib chemotherapy helps to provide long term survival.
