Editorial
Copyright ©2012 Baishideng Publishing Group Co., Limited. All rights reserved.
World J Gastrointest Surg. Dec 27, 2012; 4(12): 267-274
Published online Dec 27, 2012. doi: 10.4240/wjgs.v4.i12.267
Perioperative risk factors in patients with liver disease undergoing non-hepatic surgery
Chandra Kant Pandey, Sunaina Tejpal Karna, Vijay Kant Pandey, Manish Tandon, Amit Singhal, Vivek Mangla
Chandra Kant Pandey, Sunaina Tejpal Karna, Vijay Kant Pandey, Manish Tandon, Amit Singhal, Department of Anaesthesiology, Institute of Liver and Biliary Sciences, Vasant Kunj, New Delhi 110070, India
Vivek Mangla, Department of HPB Surgery, Institute of Liver and Biliary Sciences, Vasant Kunj, New Delhi 110070, India
Author contributions: Pandey CK collected the references; Pandey CK, Karna ST, Pandey VK, Tandon M and Singhal A contributed in writing, revising and editing the manuscript; Mangla V collected the references and edited the manuscript.
Correspondence to: Chandra Kant Pandey, MD, Professor, Head, Department of Anaesthesiology, Institute of Liver and Biliary Sciences, Sector D-1, Vasant Kunj, New Delhi 110070, India. ceekeypandey@gmail.com
Telephone: +91-95-40946851 Fax: +91-11-26123504
Received: May 11, 2012
Revised: August 25, 2012
Accepted: December 20, 2012
Published online: December 27, 2012
Abstract

The patients with liver disease present for various surgical interventions. Surgery may lead to complications in a significant proportion of these patients. These complications may result in considerable morbidity and mortality. Preoperative assessment can predict survival to some extent in patients with liver disease undergoing surgical procedures. A review of literature suggests nature and the type of surgery in these patients determines the peri-operative morbidity and mortality. Optimization of premorbid factors may help to reduce perioperative mortality and morbidity. The purpose of this review is to discuss the effect of liver disease on perioperative outcome; to understand various risk scoring systems and their prognostic significance; to delineate different preoperative variables implicated in postoperative complications and morbidity; to establish the effect of nature and type of surgery on postoperative outcome in patients with liver disease and to discuss optimal anaesthesia strategy in patients with liver disease.

Keywords: Cirrhosis; Liver disease; Perioperative risk