Dallemagne B, Perretta S, Allemann P, Donatelli G, Asakuma M, Mutter D, Marescaux J. Transgastric cholecystectomy: From the laboratory to clinical implementation. World J Gastrointest Surg 2010; 2(6): 187-192 [PMID: 21160872 DOI: 10.4240/wjgs.v2.i6.187]
Corresponding Author of This Article
Bernard Dallemagne, MD, Department of Digestive and Endocrine Surgery, Pôle Hépato-Digestif, University Hospital of Strasbourg and IRCAD, 1 Place de l’Hôpital, 67091 Strasbourg Cedex, France. bernard.dallemagne@ircad.fr
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World J Gastrointest Surg. Jun 27, 2010; 2(6): 187-192 Published online Jun 27, 2010. doi: 10.4240/wjgs.v2.i6.187
Transgastric cholecystectomy: From the laboratory to clinical implementation
Bernard Dallemagne, Silvana Perretta, Pierre Allemann, Gianfranco Donatelli, Mitsuhiro Asakuma, Didier Mutter, Jacques Marescaux
Bernard Dallemagne, Silvana Perretta, Pierre Allemann, Gianfranco Donatelli, Mitsuhiro Asakuma, Didier Mutter, Jacques Marescaux, Department of Digestive and Endocrine Surgery, Pôle Hépato-Digestif, University Hospital of Strasbourg and IRCAD, 67091 Strasbourg Cedex, France
Author contributions: Dallemagne B was principal investigator and edited the paper; Perretta S, Alleman P, Donatelli G, Asakuma M, Mutter D and Marescaux J all contributed to the performance of the surgical procedures, the data collection and the analysis and the redaction of the paper.
Correspondence to: Bernard Dallemagne, MD, Department of Digestive and Endocrine Surgery, Pôle Hépato-Digestif, University Hospital of Strasbourg and IRCAD, 1 Place de l’Hôpital, 67091 Strasbourg Cedex, France. bernard.dallemagne@ircad.fr
Telephone: +33-388-19006 Fax: +33-388-119099
Received: December 26, 2009 Revised: March 30, 2010 Accepted: May 6, 2010 Published online: June 27, 2010
Abstract
After the first report by Kalloo et al on transgastric peritoneoscopy in pigs, it rapidly became apparent that there was no room for an under-evaluated concept and blind adoption of an appealing (r)evolution in minimal access surgery. Systematic experimental work became mandatory before any translation to the clinical setting. Choice and management of the access site, techniques of dissection, exposure, retraction and tissue approximation-sealing were the basics that needed to be evaluated before considering any surgical procedure or study of the relevance of natural orifice transluminal endoscopic surgery (NOTES). After several years of testing in experimental labs, the revolutionary concept of NOTES, is now progressively being experimented on in clinical settings. In this paper the authors analyse the challenges, limitations and solutions to assess how to move from the lab to clinical implementation of transgastric endoscopic cholecystectomy.
